Fertility and Sterility
Volume 92, Issue 4 , Pages 1302-1305 , October 2009

Blastocyst transfer does not cause a sex-ratio imbalance

  • Gareth Weston, Ph.D.

      Affiliations

    • Monash IVF, Monash University, Clayton, Victoria, Australia
    • Centre for Women's Health Research, Department of Obstetrics and Gynaecology, Monash University, Clayton, Victoria, Australia
    • Corresponding Author InformationReprint requests: Gareth Weston, Ph.D., Department of Obstetrics and Gynaecology, Monash University, Level 5 Monash Medical Centre, 246–248 Clayton Road, Clayton, Victoria 3168, Australia (FAX: 61-3-9594-6389).
    • ,
  • Tiki Osianlis, Ph.D.

      Affiliations

    • Monash IVF, Monash University, Clayton, Victoria, Australia
    • ,
  • James Catt, Ph.D.

      Affiliations

    • Monash IVF, Monash University, Clayton, Victoria, Australia
    • ,
  • Beverley Vollenhoven, Ph.D.

      Affiliations

    • Monash IVF, Monash University, Clayton, Victoria, Australia
    • Centre for Women's Health Research, Department of Obstetrics and Gynaecology, Monash University, Clayton, Victoria, Australia

Received 31 May 2008 ,Revised 26 July 2008 ,Accepted 29 July 2008.

References 

  1. Staessen C, Platteau P, Van Assche E, Van Steirteghem A, Devroey P. Comparison of blastocyst transfer with or without preimplantation genetic diagnosis for aneuploidy screening in couples with advanced maternal age: a prospective randomized controlled trial. Hum Reprod. 2004;19:2849–2858
  2. Blake DA, Farquhar CM, Johnson N, Proctor M. Cleavage stage versus blastocyst stage embryo transfer in assisted conception. Cochrane Database Syst Rev. 2007;4:CD002118
  3. Ray P, Conaghan J, Winston R. Increased number of cells and metabolic activity in male human preimplantation embryos following in vitro fertilization. J Reprod Fertil. 1995;104:165–171
  4. Luna M, Duke M, Copperman A, Grunfeld L, Sandler B, Barritt J. Blastocyst embryo transfer is associated with a sex-ratio imbalance in favor of male offspring. Fertil Steril. 2007;87:519–523
  5. Borenstein M, Cohen J. Statistical power analysis: a computer program. Hillsdale (NJ): Erlbaum; 1988;
  6. Valdivia R, Kunieda T, Azuma S, Toyoda Y. PCR sexing and development rate differences in preimplantation mouse embryos fertilized and cultured in vitro. Mol Reprod Dev. 1993;35:121–126
  7. Richter K, Anderson M, Osborn B. Selection for faster development does not bias sex ratios resulting from blastocyst embryo transfer. Reprod Biomed Online. 2006;12:460–465

 G.W. has nothing to disclose. T.O. has nothing to disclose. J.C. has nothing to disclose. B.V. has nothing to disclose.

PII: S0015-0282(08)03567-X

doi: 10.1016/j.fertnstert.2008.07.1784

Fertility and Sterility
Volume 92, Issue 4 , Pages 1302-1305 , October 2009

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