Fertility and Sterility
Volume 92, Issue 4 , Pages 1264-1268 , October 2009

Stimulation of endometrium embryo transfer can improve implantation and pregnancy rates for patients undergoing assisted reproductive technology for the first time with a high-grade blastocyst

  • Sakae Goto, M.D., Ph.D.

      Affiliations

    • Hanabusa Women's Clinic, Kobe, Japan
    • Corresponding Author InformationReprint requests: Sakae Goto, M.D., Ph.D., Hanabusa Women's Clinic, Chuo-ku, Sannomiya-cho 1-1-2, Sannomiya central building 2F, Kobe, Hyogo, Japan 650-0021 (FAX: 81-78-392-8718).
    • ,
  • Takashi Kadowaki, M.D., M.P.H., Ph.D.

      Affiliations

    • Department of Health Science, Shiga University of Medical Science, Otsu, Japan
    • ,
  • Hiromi Hashimoto, B.S.

      Affiliations

    • Hanabusa Women's Clinic, Kobe, Japan
    • ,
  • Shoji Kokeguchi, M.D., Ph.D.

      Affiliations

    • Hanabusa Women's Clinic, Kobe, Japan
    • ,
  • Masahide Shiotani, M.D., Ph.D.

      Affiliations

    • Hanabusa Women's Clinic, Kobe, Japan

Received 16 April 2008 ,Revised 27 June 2008 ,Accepted 1 August 2008.

References 

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  2. Tazuke SI, Giudice LC. Growth factors and cytokines in endometrium, embryonic development, and maternal: embryonic interactions. Semin Reprod Endocrinol. 1996;14:231–245
  3. Simon C, Gimeno MJ, Mercader A, O'Connor JE, Remohi J, Polan ML, et al. Embryonic regulation of integrins beta 3, alpha 4, and alpha 1 in human endometrial epithelial cells in vitro. J Clin Endocrinol Metab. 1997;82:2607–2616
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  8. Perrier d'Hauterive S, Charlet-Renard C, Berndt S, Dubois M, Munaut C, Goffin F, et al. Human chorionic gonadotropin and growth factors at the embryonic-endometrial interface control leukemia inhibitory factor (LIF) and interleukin 6 (IL-6) secretion by human endometrial epithelium. Hum Reprod. 2004;19:2633–2643
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  10. Goto S, Kadowaki T, Hashimoto H, Kokeguchi S, Shiotani M. Stimulation of endometrium embryo transfer (SEET): injection of embryo culture supernatant into the uterine cavity before blastocyst transfer can improve implantation and pregnancy rates. Fertil Steril. 2007;88:1339–1343
  11. Goto S, Shiotani M, Kitagawa M, Kadowaki T, Noda Y. Effectiveness of two-step (consecutive) embryo transfer in patients who have two embryos on day 2: comparison with cleavage-stage embryo transfer. Fertil Steril. 2005;83:721–723
  12. Goto S, Takebayashi K, Shiotani M, Fujiwara M, Hirose M, Noda Y. Effectiveness of 2-step (consecutive) embryo transfer. Comparison with cleavage-stage transfer. J Reprod Med. 2003;48:370–374
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  16. Wakuda K, Takakura K, Nakanishi K, Kita N, Shi H, Hirose M, et al. Embryo-dependent induction of embryo receptivity in the mouse endometrium. J Reprod Fertil. 1999;115:315–324
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  18. Choi YH, Love LB, Varner DD, Hinrichs K. Effect of holding technique and culture drop size in individual or group culture on blastocyst development after ICSI of equine oocytes with low meiotic competence. Anim Reprod Sci. 2007;102:38–47
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 S.G. has nothing to disclose. T.K. has nothing to disclose. H.H. has nothing to disclose. S.K. has nothing to disclose. M.S. has nothing to disclose.

PII: S0015-0282(08)03570-X

doi: 10.1016/j.fertnstert.2008.08.076

Fertility and Sterility
Volume 92, Issue 4 , Pages 1264-1268 , October 2009

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