Fertility and Sterility
Volume 91, Issue 3 , Pages 929.e5-929.e7 , March 2009

Careful cardiovascular screening and follow-up of women with Turner syndrome before and during pregnancy is necessary to prevent maternal mortality

  • Celine Chalas Boissonnas, M.D.

      Affiliations

    • Laboratoire de Biologie de la Reproduction-CECOS, Groupe Hospitalier Cochin- Saint-Vincent de Paul, Assistance Publique-Hôpitaux de Paris, Université René Descartes, Paris, France
    • Corresponding Author InformationReprint requests: Celine Chalas Boissonnas, M.D., Hopital Cochin, Service de Biologie de la Reproduction, 123 Boulevard de Port Royal, 75014 Paris, France (FAX: 33158411565).
    • ,
  • Celine Davy, M.D.

      Affiliations

    • Service de Médecine de la Reproduction, Groupe Hospitalier Cochin- Saint-Vincent de Paul, Assistance Publique-Hôpitaux de Paris, Université René Descartes, Paris, France
    • Maternité Port Royal, Groupe Hospitalier Cochin- Saint-Vincent de Paul, Assistance Publique-Hôpitaux de Paris, Université René Descartes, Paris, France
    • ,
  • Marie Bornes, M.D.

      Affiliations

    • Maternité Port Royal, Groupe Hospitalier Cochin- Saint-Vincent de Paul, Assistance Publique-Hôpitaux de Paris, Université René Descartes, Paris, France
    • ,
  • Leila Arnaout, M.D.

      Affiliations

    • Département d'Anesthésie Réanimation, Groupe Hospitalier Cochin- Saint-Vincent de Paul, Assistance Publique-Hôpitaux de Paris, Université René Descartes, Paris, France
    • ,
  • Christophe Meune, M.D., Ph.D.

      Affiliations

    • Service de Cardiologie, Groupe Hospitalier Cochin- Saint-Vincent de Paul, Assistance Publique-Hôpitaux de Paris, Université René Descartes, Paris, France
    • ,
  • Vassilis Tsatsatris, M.D., Ph.D.

      Affiliations

    • Maternité Port Royal, Groupe Hospitalier Cochin- Saint-Vincent de Paul, Assistance Publique-Hôpitaux de Paris, Université René Descartes, Paris, France
    • ,
  • Alexandre Mignon, M.D., Ph.D.

      Affiliations

    • Département d'Anesthésie Réanimation, Groupe Hospitalier Cochin- Saint-Vincent de Paul, Assistance Publique-Hôpitaux de Paris, Université René Descartes, Paris, France
    • ,
  • Pierre Jouannet, M.D.

      Affiliations

    • Laboratoire de Biologie de la Reproduction-CECOS, Groupe Hospitalier Cochin- Saint-Vincent de Paul, Assistance Publique-Hôpitaux de Paris, Université René Descartes, Paris, France

Received 28 July 2008 ,Revised 4 September 2008 ,Accepted 6 September 2008.

References 

  1. Press F, Shapiro HM, Cowell CA, Oliver GD. Outcome of ovum donation in Turner's syndrome patients. Fertil Steril. 1995;64:995–998
  2. Saenger P, Albertsson Wikland K, Conway GS, Davenport M, Gravholt CH, Hintz R, et al. Recommendations for the diagnosis and management of Turner syndrome. J Clin Endocrinol Metab. 2001;86:3061–3069
  3. Rosenwaks Z, Veeck LL, Liu HC. Pregnancy following transfer of in vitro fertilized donated oocytes. Fertil Steril. 1986;45:417–420
  4. Devroey P, Braeckmans P, Camus M, Khan I, Smitz J, Staessen C, et al. Embryo donation in patients with primary ovarian failure. Hum Reprod. 1988;3(Suppl 2):85–87
  5. Foudila T, Söderström-Anttila V, Hovatta O. Turner's syndrome and pregnancies after oocyte donation. Hum Reprod. 1999;14:532–535
  6. Bodri D, Vernaeve V, Figueras F, Vidal R, Guillén JJ, Coll O. Oocyte donation in patients with Turner's syndrome: a successful technique but with an accompanying high risk of hypertensive disorders during pregnancy. Hum Reprod. 2006;21:829–832
  7. Nagel TC, Tesch LG. ART and high risk patients!. Fertil Steril. 1997;68:748–749
  8. Beauchesne LM, Connolly HM, Ammash NM, Warnes CA. Coarctation of the aorta: outcome of pregnancy. J Am Coll Cardiol. 2001;38:1728–1733
  9. Garvey P, Elovitz M, Landsberger EJ. Aortic dissection and myocardial infarction in a pregnant patient with Turner syndrome. Obstet Gynecol. 1998;91:864
  10. Practice Committee of the American Society for Reproductive Medicine. Increased maternal cardiovascular mortality associated with pregnancy in women with Turner syndrome. Fertil Steril. 2006;86(5 Suppl):S127–S128
  11. Carlson M, Silberbach M. Dissection of the aorta in Turner syndrome: two new cases and review of 85 cases in the literature. J Med Genet. 2007;44:745–749
  12. Immer FF, Bansi AG, Immer-Bansi AS, McDougall J, Zehr KJ, Schaff HV, et al. Aortic dissection in pregnancy: analysis of risk factors and outcome. Ann Thorac Surg. 2003;76:309
  13. Matura LA, Ho VB, Rosing DR, Bondy CA. Aortic dilatation and dissection in Turner syndrome. Circulation. 2007;116:1663–1670
  14. Bondy CA. Turner Syndrome Study Group. Care of girls and women with Turner syndrome: a guideline of the Turner Syndrome Study Group. J Clin Endocrinol Metab. 2007;92:10–25
  15. Ostberg JE, Brookes JA, McCarthy C, Halcox J, Conway GS. A comparison of echocardiography and magnetic resonance imaging in cardiovascular screening of adults with Turner syndrome. J Clin Endocrinol Metab. 2004;89:5966–5971
  16. Karnis MF, Zimon AE, Lalwani SI, Timmreck LS, Klipstein S, Reindollar RH. Risk of death in pregnancy achieved through oocyte donation in patients with Turner syndrome: a national survey. Fertil Steril. 2003;80:498–501
  17. Landin-Wilhelmsen K, Bryman I, Hanson C, Hanson L. Spontaneous pregnancies in a Turner syndrome woman with Y-chromosome mosaicism. J Assist Reprod Genet. 2004;21:229–230

 C.C.B. has nothing to disclose. C.D. has nothing to disclose. M.B. has nothing to disclose. L.A. has nothing to disclose. C.M. has nothing to disclose. V.T. has nothing to disclose. A.M. has nothing to disclose. P.J. has nothing to disclose.

PII: S0015-0282(08)03943-5

doi: 10.1016/j.fertnstert.2008.09.037

Fertility and Sterility
Volume 91, Issue 3 , Pages 929.e5-929.e7 , March 2009

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