Fertility and Sterility
Volume 93, Issue 1 , Pages 239-250, 1 January 2010

Gene therapy targeting leiomyoma: adenovirus-mediated delivery of dominant-negative estrogen receptor gene shrinks uterine tumors in Eker rat model

  • Memy H. Hassan, M.Sc.

      Affiliations

    • Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, Texas
    • Department of Pharmacology and Toxicology, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt
    • ,
  • Salama A. Salama, Ph.D.

      Affiliations

    • Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, Texas
    • ,
  • Dong Zhang, Ph.D.

      Affiliations

    • Department of Carcinogenesis, M. D. Anderson Cancer Center, University of Texas, Texas
    • Center for Women Health Research, Department of Obstetrics and Gynecology, Meharry Medical College, Nashville, Tennessee
    • ,
  • Hossam M.M. Arafa, Ph.D.

      Affiliations

    • Department of Pharmacology and Toxicology, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt
    • ,
  • Farid M.A. Hamada, Ph.D.

      Affiliations

    • Department of Pharmacology and Toxicology, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt
    • ,
  • Hala Fouad, M.D., Ph.D.

      Affiliations

    • Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, Texas
    • ,
  • Cheryl C. Walker, Ph.D.

      Affiliations

    • Department of Carcinogenesis, M. D. Anderson Cancer Center, University of Texas, Texas
    • ,
  • Ayman Al-Hendy, M.D., Ph.D.

      Affiliations

    • Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, Texas
    • Center for Women Health Research, Department of Obstetrics and Gynecology, Meharry Medical College, Nashville, Tennessee
    • Corresponding Author InformationReprint requests: Ayman Al-Hendy, Professor and Vice Chair, Center for Women Health Research, Department of Obstetrics and Gynecology, Meharry Medical College, 1005 Dr. D. B. Todd Jr. Blvd., Nashville, Tennessee 37208 (FAX: 615-963-3125).

Received 6 September 2008; received in revised form 23 September 2008; accepted 30 September 2008. published online 14 January 2009.

To access this article, please choose from the options below

Login to an existing account or Register a new account.

  • Purchase this article for 31.50 USD (You must login/register to purchase this article)

    Online access for 24 hours. The PDF version can be downloaded as your permanent record.

  • Subscribe to this title

    Get unlimited online access to this article and all other articles in this title 24/7 for one year.

  • Claim access now

    For current subscribers with Society Membership or Account Number.

  • Visit SciVerse ScienceDirect to see if you have access via your institution.

 M.H. has nothing to disclose. S.S. has nothing to disclose. D.Z. has nothing to disclose. H.A. has nothing to disclose. F.H. has nothing to disclose. H.F. has nothing to disclose. C.W. has nothing to disclose. A.A.-H. has nothing to disclose.

 Supported by National Institutes of Health/National Institute of Child Health and Human Development grant no. R01 HD046228-01.

PII: S0015-0282(08)04127-7

doi:10.1016/j.fertnstert.2008.09.086

Fertility and Sterility
Volume 93, Issue 1 , Pages 239-250, 1 January 2010

Article Tools

* Image Usage & Resolution