Fertility and Sterility
Volume 93, Issue 3 , Pages 702-705 , February 2010

Human chorionic gonadotropin ratio of hemoperitoneum versus venous serum improves early diagnosis of ectopic pregnancy

  • YuDong Wang, M.D.

      Affiliations

    • Department of Obstetrics and Gynecology, the Sixth People's Hospital, Shanghai Jiaotong University, Shanghai, People's Republic of China
    • ,
  • Hong Zhao, Ph.D.

      Affiliations

    • Department of Radiology and Pathology, the Methodist Hospital, Weill Medical College, Cornell University, Houston, Texas
    • ,
  • YinCheng Teng, M.D.

      Affiliations

    • Department of Obstetrics and Gynecology, the Sixth People's Hospital, Shanghai Jiaotong University, Shanghai, People's Republic of China
    • Corresponding Author InformationReprint requests: YinCheng Teng, Department of Obstetrics and Gynecology, the Sixth People's Hospital, Shanghai Jiaotong University, Shanghai 200233, People's Republic of China (FAX: 0086-021-64701361).
    • ,
  • LiHua Lu, B.A.

      Affiliations

    • Department of Obstetrics and Gynecology, the Sixth People's Hospital, Shanghai Jiaotong University, Shanghai, People's Republic of China
    • ,
  • JianQian Tong, B.A.

      Affiliations

    • Department of Obstetrics and Gynecology, the Sixth People's Hospital, Shanghai Jiaotong University, Shanghai, People's Republic of China

Received 15 July 2008 ,Revised 7 October 2008 ,Accepted 11 October 2008.

References 

  1. Obed SA, Wilson JB, Elkins TE. Diagnosing unruptured ectopic pregnancy. Int J Gynecol Obstet. 1994;45:21–25
  2. Dimitry ES. A ten year survey of 193 ectopic pregnancies. J Obstet Gynecol. 1989;9:309–313
  3. Ander DS, Ward KR. Medical management of ectopic pregnancy—the role of methotrexate. J Emerg Med. 1997;15:177–182
  4. Mol BW, van der Veen F, Bossuyt PM. Symptom-free women at increased risk of ectopic pregnancy: should we screen?. Acta Obstet Gynecol Scand. 2002;81:661–672
  5. Job-Spira N, Fernandez H, Bouyer J, Pouly JL, Germain E, Coste J. Ruptured tubal ectopic pregnancy: risk factors and reproductive outcome: results of a population-based study in France. Am J Obstet Gynecol. 1999;180:938–944
  6. Fauconnier A, Mabrouk A, Heitz D, Ville Y. Ectopic pregnancy: interest and value of clinical examination in management policy. J Gynecol Obstet Biol Reprod (Paris). 2003;32(7 Suppl):18–27
  7. Kaplan BC, Dart RG, Moskos M, Kuligowska E, Chun B, Adel Hamid M, et al. Ectopic pregnancy: prospective study with improved diagnostic accuracy. Ann Emerg Med. 1996;28:10–17
  8. Mol BW, Hajenius PJ, Engelsbel S, Ankum WM, Van der Veen F, Hemrika DJ, et al. Serum human chorionic gonadotropin measurement in the diagnosis of ectopic pregnancy when transvaginal sonography is inconclusive. Fertil Steril. 1998;70:972–981
  9. Pisarska MD, Casson PR, Moise KJ, DiMaio DJ, Buster JE, Carson SA. Heterotopic abdominal pregnancy treated at laparoscopy. Fertil Steril. 1998;70:159–160
  10. Barnhart KT, Simhan H, Kamelle SA. Diagnostic accuracy of ultrasound above and below the hCG discriminatory zone. Obstet Gynecol. 1999;94:583–587
  11. Garcia CR, Barnhart KT. Diagnosing ectopic pregnancy: decision analysis comparing six strategies. Obstet Gynecol. 2001;97:464–470
  12. Hsieh BC, Hwang JL, Pan HS, Huang SC, Chen CY, Chen PH. Heterotopic caesarean scar pregnancy combined with intrauterine pregnancy successfully treated with embryo aspiration for selective embryo reduction case report. Hum Reprod. 2004;19:285–287
  13. Chang Y, Lee JN, Yang CH, Hsu SC, Tsai EM. An unexpected quadruplet heterotopic pregnancy after bilateral salpinguectomy and replacement of three embryos. Fertil Steril. 2003;80:218–222
  14. Barrenetxea G, Barinaga-Rementeria L, Lopez de Larruzea A, Agirregoikoa JA, Mandiola M, Carbonero K. Heterotopic pregnancy: two cases and a comparative review. Fertil Steril. 2007;87:417
  15. Cheng PJ, Chueh HY, Qiu JT. Heterotopic pregnancy in a natural conception cycle presenting as hematometra. Obstet Gynecol. 2004;104:1195–1198
  16. Oliveira FG, Abdelmassih V, Costa AL, Balmaceda JP, Abdelmassih S, Abdelmassih R. Rare association of ovarian implantation site for patients with heterotpic and with primary ectopic pregnancies after ICSI and blastocyst transfer. Hum Reprod. 2001;16:2227–2229
  17. Habana A, Dokras A, Giraldo JL, Jones EE. Cornual heterotopic pregnancy: contemporary management options. Am J Obstet Gynecol. 2000;182:1264–1270
  18. Swire MN, Castro-Aragon I, Levine D. Various sonographic appearances of the hemorrhagic corpus luteum cyst. Ultrasound Q. 2004;20:45–58
  19. Atri M. Ectopic pregnancy versus corpus luteum cyst revisited: best Doppler predictors. J Ultrasound Med. 2003;22:1181–1184
  20. Daponte A, Pournaras S, Zintzaras E, Kallitsaris A, Lialios G, Maniatis AN, et al. The value of a single combined measurement of VEGF, glycodelin, progesterone, PAPP-A, HPL and LIF for differentiating between ectopic and abnormal intrauterine pregnancy. Hum Reprod. 2005;20:3163–3166
  21. Condous G, Kirk E, Syed A, Van Calster B, Van Huffel S, Timmerman D, et al. Do levels of serum cancer antigen 125 and creatine kinase predict the outcome in pregnancies of unknown location?. Hum Reprod. 2005;20:3348–3354

 The first two authors contributed equally to this work.

 Y.D.W. has nothing to disclose. H.Z. has nothing to disclose. Y.C.T. has nothing to disclose. L.H.L. has nothing to disclose. J.Q.T. has nothing to disclose.

 This study was supported by the Foundation of the Sixth People's Hospital, Shanghai Jiaotong University, China, grant no. 0875 (to Y.D.W.).

PII: S0015-0282(08)04206-4

doi: 10.1016/j.fertnstert.2008.10.013

Fertility and Sterility
Volume 93, Issue 3 , Pages 702-705 , February 2010

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