Fertility and Sterility
Volume 93, Issue 3 , Pages 802-806 , February 2010

Human papillomavirus found in sperm head of young adult males affects the progressive motility

  • Carlo Foresta, M.D.

      Affiliations

    • Department of Histology, Microbiology and Medical Biotechnologies, Section of Clinical Pathology and Centre for Male Gamete Cryopreservation, University of Padova, Italy
    • Corresponding Author InformationReprint requests: Prof. Carlo Foresta, University of Padova, Department of Histology, Microbiology and Medical Biotechnologies, Section of Clinical Pathology and Centre for Male Gamete Cryopreservation, Via Gabelli 63 - 35121 Padova, Italy (TEL: +39 049 8218517; FAX: +39 049 8218520).
    • ,
  • Andrea Garolla, M.D.

      Affiliations

    • Department of Histology, Microbiology and Medical Biotechnologies, Section of Clinical Pathology and Centre for Male Gamete Cryopreservation, University of Padova, Italy
    • ,
  • Daniela Zuccarello, M.D.

      Affiliations

    • Department of Histology, Microbiology and Medical Biotechnologies, Section of Clinical Pathology and Centre for Male Gamete Cryopreservation, University of Padova, Italy
    • ,
  • Damiano Pizzol, M.S.

      Affiliations

    • Department of Histology, Microbiology and Medical Biotechnologies, Section of Clinical Pathology and Centre for Male Gamete Cryopreservation, University of Padova, Italy
    • ,
  • Afra Moretti, B.Sc.

      Affiliations

    • Department of Histology, Microbiology and Medical Biotechnologies, Section of Clinical Pathology and Centre for Male Gamete Cryopreservation, University of Padova, Italy
    • ,
  • Luisa Barzon, M.D.

      Affiliations

    • Department of Histology, Microbiology and Medical Biotechnologies, Section of Microbiology and Medical Biotechnologies, University of Padova, Italy
    • ,
  • Giorgio Palù, M.D.

      Affiliations

    • Department of Histology, Microbiology and Medical Biotechnologies, Section of Microbiology and Medical Biotechnologies, University of Padova, Italy

Received 18 August 2008 ,Revised 14 October 2008 ,Accepted 16 October 2008.

References 

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  4. Nielson CM, Harris RB, Dunne EF, Abrahamsen M, Papenfuss MR, Flores R, et al. Risk factors for anogenital human papillomavirus infection in men. J Infect Dis. 2007;196:1137–1145
  5. Palefsky JM. HPV infection in men. Dis Markers. 2007;23:261–272
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  8. Nielson CM, Flores R, Harris RB, Abrahamsen M, Papenfuss MR, Dunne EF, et al. Human papillomavirus prevalence and type distribution in male anogenital sites and semen. Cancer Epidemiol Biomarkers Prev. 2007;16:1107–1114
  9. Svec A, Mikysková I, Hes O, Tachezy R. Human papillomavirus infection of the epididymis and ductus deferens: an evaluation by nested polymerase chain reaction. Arch Pathol Lab Med. 2003;127:1471–1474
  10. Martorell M, Gil-Salom M, Pérez-Vallés A, Garcia JA, Rausell N, Senpere A. Presence of human papillomavirus DNA in testicular biopsies from nonobstructive azoospermic men. Arch Pathol Lab Med. 2005;129:1132–1136
  11. Rintala MA, Grénman SE, Pöllänen PP, Suominen JJ, Syrjänen SM. Detection of high-risk HPV DNA in semen and its association with the quality of semen. Int J STD AIDS. 2004;15:740–743
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  13. World Health Organization. WHO laboratory manual for the examination of human semen and sperm-cervical mucus interaction. Cambridge: Cambridge University Press; 1999;
  14. Manos MM, Ting Y, Wright DK, Lewis AJ, Broker TR. Use of polymerase chain reaction amplification for the detection of genital human papillomaviruses. Cancer Cells. 1989;7:209–214
  15. Jacobs MV, de Roda Husman AM, van den Brule AJ, Snijders PJ, Meijer CJ, Walboomers JM. Group-specific differentiation between high- and low-risk human papillomavirus genotypes by general primer-mediated PCR reaction and two cocktails of oligonucleiotide probes. J Clin Microbiol. 1995;33:901–905
  16. Biasolo MA, Calistri A, Cesaro S, Gentile G, Mengoli C, Palù G. Case report: kinetics of Epstein-Barr virus load in a bone marrow transplant patient with no sign of lymphoproliferative disease. J Med Virol. 2003;69:220–224
  17. Dinh TH, Sternberg M, Dunne EF, Markowitz LE. Genital warts among 18- to 59-year-olds in the United States, national health and nutrition examination survey, 1999–2004. Sex Transm Dis. 2008;35:357–360
  18. Heideman DA, Waterboer T, Pawlita M, Delis-van Diemen P, Nindl I, Leijte JA, et al. Human papillomavirus-16 is the predominant type etiologically involved in penile squamous cell carcinoma. J Clin Oncol. 2007;25:4550–4556
  19. Bosch FX, de Sanjosé S. The epidemiology of human papillomavirus infection and cervical cancer. Dis Markers. 2007;23:213–227
  20. Smith JS, Melendy A, Rana RK, Pimenta JM. Age-specific prevalence of infection with human papillomavirus in females: a global review. J Adolesc Health. 2008;43:S5–25
  21. Lai YM, Yang FP, Pao CC. Human papillomavirus deoxyribonucleic acid and ribonucleic acid in seminal plasma and sperm cells. Fertil Steril. 1996;65:1026–1030
  22. Lee CA, Huang CT, King A, Chan PJ. Differential effects of human papillomavirus DNA types on p53 tumor-suppressor gene apoptosis in sperm. Gynecol Oncol. 2002;85:511–516
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 C.F. has nothing to disclose. A.G. has nothing to disclose. D.Z. has nothing to disclose. D.P. has nothing to disclose. A.M. has nothing to disclose. L.B. has nothing to disclose. G.P. has nothing to disclose.

PII: S0015-0282(08)04408-7

doi: 10.1016/j.fertnstert.2008.10.050

Fertility and Sterility
Volume 93, Issue 3 , Pages 802-806 , February 2010

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