Fertility and Sterility
Volume 93, Issue 3 , Pages 769-773 , February 2010

Beneficial effect of autologous endometrial cell coculture in patients with repeated implantation failure

Received 7 May 2008 ,Revised 22 October 2008 ,Accepted 29 October 2008.

References 

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  2. Barmat LI, Liu HC, Spandorfer SD, Veek l, Damario M, Rosenwaks Z. Human preembryo development on autologous endometrial coculture versus conventional medium. Fertil Steril. 1998;70:1109–1113
  3. Dirnfeld M, Goldman S, Gonene Y, Koifman M, Calderon I, Abramovici H. A simplified coculture system with luteinized granulosa cells improves embryo quality and implantation rates: a controlled study. Fertil Steril. 1997;67:120–122
  4. Feng HL, Wen XH, Amet T, Pesser SC. Effect of different coculture systems in early human embryo development. Hum Reprod. 1996;11:1525–1528
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  10. Spandorfer SD, Pascal P, Parks J, Clark R, Veeck L, Davis OK, et al. Autologous endometrial co-culture in patients with IVF failures: outcome of the first 1030 cases. J Reprod Med. 2004;49:463–467
  11. Spandorfer S, Park J, Davis O, Clarke R, Rosenwaks Z. A case controlled study evaluating autologous endometrial coculture (AECC) as an effective tool for young patients (age<36 years) with multiple failed IVF attempts and diminished ovarian reserve. Fertil Steril. 2007;88(Suppl 1):O-275
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  14. Menezo Y, Guerin J, Czyba J. Improvement of early human embryo development in vitro by coculture on monolayers of Vero cells. Biol Reprod. 1990;42:301–306
  15. Nieto F, Watkins W, Lopata A, Baker G, Edgar D. The effect of coculture with autologous cryopreserved endometrial cells on human in vitro fertilization and early embryo morphology: a randomized study. J Assist Reprod Genet. 1996;13:386–389
  16. Simon C, Pellicer A. Interleukin-1 system crosstalk between embryo and endometrium in implantation. Hum Reprod. 1995;10(Suppl 1):11
  17. Spandorfer SD, Barnat LI, Liu HC, Mele C, Veeck L, Rosenwaks Z. Granulocyte macrophage stimulating factor production by autologous endometrial co-culture is associated with outcome for IVF patient with a history of multiple implantation failures. Am J Reprod Immunol. 1998;40:377–381
  18. Spandorfer SD, Neuer A, Liu HC, Bivis L, Clarke R, Veeck L, et al. Interleukin-1 levels in the supernatant of conditioned media of embryos grown in autologous endometrial co-culture: correlation with embryonic development and outcome for patient with a history of multiple implantation failures. Am J Reprod Immunol. 2000;42:6–11
  19. Spandorfer SD, Navarro J, Levy D, Black AQR, Liu HC, Veeck L, et al. Autologous endometrial co-culture in patient with IVF failures: correlation of outcome with leukemia inhibiting factor (LIF) production. Am J Reprod Immunol. 2001;46:375–380
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 V.E. has nothing to disclose. F.G.E.R. has nothing to disclose. M.P. has nothing to disclose. J.B. has nothing to disclose. C.G. has nothing to disclose. J.B. has nothing to disclose.

 Supported in part by Grant ANR 600 NA 002/06 from FONTAR, Agencia Nacional de Promoción Científica y Tecnológica, Argentina.

PII: S0015-0282(08)04421-X

doi: 10.1016/j.fertnstert.2008.10.060

Fertility and Sterility
Volume 93, Issue 3 , Pages 769-773 , February 2010

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