Fertility and Sterility
Volume 93, Issue 4 , Pages 1286-1289 , 1 March 2010

Conservative surgical management of stage IA endometrial carcinoma for fertility preservation

  • Ivan Mazzon, M.D.

      Affiliations

    • Endoscopic Gynecologic Unit, Nuova Villa Claudia, Rome, Italy
    • Corresponding Author InformationReprint requests: Ivan Mazzon, M.D., Endoscopic Gynecologic Unit, Nuova Villa Claudia, Via Flaminia Nuova, 280-00191 Rome, Italy (FAX: 39-06-36303751).
    • ,
  • Giacomo Corrado, M.D., Ph.D.

      Affiliations

    • Department of Oncology, Catholic University of the Sacred Heart, Campobasso, Italy
    • ,
  • Valeria Masciullo, M.D., Ph.D.

      Affiliations

    • Division of Gynecologic Oncology, Catholic University of the Sacred Heart, Rome, Italy
    • ,
  • Daniela Morricone, M.D.

      Affiliations

    • Endoscopic Gynecologic Unit, Nuova Villa Claudia, Rome, Italy
    • ,
  • Gabriella Ferrandina, M.D.

      Affiliations

    • Department of Oncology, Catholic University of the Sacred Heart, Campobasso, Italy
    • ,
  • Giovanni Scambia, M.D.

      Affiliations

    • Division of Gynecologic Oncology, Catholic University of the Sacred Heart, Rome, Italy

Received 4 December 2007 ,Revised 13 November 2008 ,Accepted 8 December 2008.

References 

  1. ACOG Practice Bulletin, Number 65, August 2005. Management of endometrial cancer. Obstet Gynecol. 2005;106:413–425
  2. Duska LR, Garrett A, Rueda BR, Haas J, Chang Y, Fuller AF. Endometrial cancer in women 40 years old or younger. Gynecol Oncol. 2001;83:388–393
  3. International Federation of Gynecology and Obstetrics annual report on the results of treatment in gynecologic cancer. Int J Gynecol Obstet. 1989;28:189–193
  4. Kim YB, Holschneider CH, Ghosh K, Nieberg RK, Montz FJ. Progestin alone as primary treatment of endometrial carcinoma in premenopausal women. Report of seven cases and review of the literature. Cancer. 1997;79:320–327
  5. Ramirez PT, Frumovitz M, Bodurka DC, Sun CC, Levenback C. Hormonal therapy for the management of grade 1 endometrial adenocarcinoma: a literature review. Gynecol Oncol. 2004;95:133–138
  6. Yang YC, Wu CC, Chen CP, Chang CL, Wang KL. Reevaluating the safety of fertility-sparing hormonal therapy for early endometrial cancer. Gynecol Oncol. 2005;99:287–293
  7. Pinto AB, Gopal M, Herzog TJ, Pfeifer JD, Williams DB. Successful in vitro fertilization pregnancy after conservative management of endometrial cancer. Fertil Steril. 2001;76:826–829
  8. Kurman RJ, Norris HJ. Evaluation of criteria for distinguishing atypical endometrial hyperplasia from well-differentiated carcinoma. Cancer. 1982;49:2547–2559
  9. Vinker S, Shani A, Open M, Fenig E, Dgani R. Conservative treatment of adenocarcinoma of the endometrium in young patients. Is it appropriate?. Eur J Obstet Gynecol Reprod Biol. 1999;83:63–65
  10. Niwa K, Tagami K, Lian Z, Onogi K, Mori H, Tamaya T. Outcome of fertility-preserving treatment in young women with endometrial carcinomas. BJOG. 2005;112:317–320
  11. Mazzon I, Corrado G, Morricone D, Scambia G. Reproductive preservation for treatment of stage IA endometrial cancer in a young woman: hysteroscopic resection. Int J Gynecol Cancer. 2005;15:974–978
  12. Randall TC, Kurman RJ. Progestin treatment of atypical hyperplasia and well-differentiated carcinoma of the endometrium in women under age 40. Obstet Gynecol. 1997;90:434–440
  13. Lowe MP, Cooper BC, Sood AK, Davis WA, Syrop CH, Sorosky JI. Implementation of assisted reproductive technologies following conservative management of FIGO grade I endometrial adenocarcinoma and/or complex hyperplasia with atypia. Gynecol Oncol. 2003;91:569–572
  14. Ben-Shachar I, Vitellas KM, Cohn DE. The role of MRI in the conservative management of endometrial cancer. Gynecol Oncol. 2004;93:233–237
  15. Savelli L, Ceccarini M, Ludovisi M, Fruscella E, De Iaco PA, Salizzoni E, et al. Preoperative local staging of endometrial cancer: transvaginal sonography vs magnetic resonance imaging. Ultrasound Obstet Gynecol. 2008;31:560–566
  16. Shveiky D, Rojansky N, Revel A, Benshuschan A, Laufer N, Shushan A. Complications of hysteroscopic surgery: “beyond the learning curve”. J Minim Invasive Gynecol. 2007;14:218–222
  17. Lo KW, Cheung TH, Yim SF, Chung TK. Hysteroscopic dissemination of endometrial carcinoma using carbon dioxide and normal saline: a retrospective study. Gynecol Oncol. 2002;84:394–398
  18. Kadar N, Homesley HD, Malfetano JH. Positive peritoneal cytology is an adverse factor in endometrial carcinoma only if there is other evidence of extrauterine disease. Gynecol Oncol. 1992;46:145–149

 I.M. has nothing to disclose. G.C. has nothing to disclose. V.M. has nothing to disclose. D.M. has nothing to disclose. G.F. has nothing to disclose. G.S. has nothing to disclose.

PII: S0015-0282(08)04656-6

doi: 10.1016/j.fertnstert.2008.12.009

Fertility and Sterility
Volume 93, Issue 4 , Pages 1286-1289 , 1 March 2010

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