Fertility and Sterility
Volume 93, Issue 4 , Pages 1112-1123 , 1 March 2010

PCSK4-null sperm display enhanced protein tyrosine phosphorylation and ADAM2 proteolytic processing during in vitro capacitation

  • Charles Gyamera-Acheampong, M.Sc.

      Affiliations

    • Chronic Disease Program, Ottawa Health Research Institute, Ottawa, Ontario, Canada
    • Department of Biochemistry, Microbiology, and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada
  • ,
  • Julian Vasilescu, M.Sc.

      Affiliations

    • Department of Biochemistry, Microbiology, and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada
    • Institute of Systems Biology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada
  • ,
  • Daniel Figeys, Ph.D.

      Affiliations

    • Department of Biochemistry, Microbiology, and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada
    • Institute of Systems Biology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada
  • ,
  • Majambu Mbikay, Ph.D.

      Affiliations

    • Chronic Disease Program, Ottawa Health Research Institute, Ottawa, Ontario, Canada
    • Department of Biochemistry, Microbiology, and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada
    • Division of Endocrinology, Ottawa Hospital, Ottawa, Ontario, Canada
    • Corresponding Author InformationReprint requests: Dr. Majambu Mbikay, Ottawa Health Research Institute, 725 Parkdale Avenue, Ottawa, Ontario, Canada K1Y 4E9 (FAX: 613-761-4355).

Received 8 August 2008 ,Revised 31 October 2008 ,Accepted 10 December 2008.

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 C.G.-A. has nothing to disclose. J.V. has nothing to disclose. D.F. has nothing to disclose. M.M. has nothing to disclose.

 Supported by the Natural Sciences and Engineering Council of Canada.

PII: S0015-0282(08)04685-2

doi: 10.1016/j.fertnstert.2008.12.013

Fertility and Sterility
Volume 93, Issue 4 , Pages 1112-1123 , 1 March 2010