In vitro fertilization pregnancy in a patient with proven chronic endometritis

Received 20 October 2008; received in revised form 24 November 2008; accepted 10 December 2008. published online 20 January 2009.

Objective

To report an in vitro fertilization (IVF) pregnancy in a patient with histologically confirmed chronic endometritis before the IVF treatment without prior antibiotherapy.

Design

Case report.

Setting

Academic reproductive medicine unit.

Patient(s)

A 30-year-old woman with primary infertility due to mild oligoasthenoteratospermia of the male partner.

Intervention(s)

Diagnostic hysteroscopy and endometrial biopsy.

Main Outcome Measure(s)

Delivery after the first IVF.

Result(s)

Histologic examination of the endometrium revealed chronic endometritis. The patient delivered a healthy boy at 40 weeks' gestation after the first IVF treatment.

Conclusion(s)

Our findings suggest that the impact of chronic endometritis on infertility and IVF outcome should be further investigated in prospective randomized studies.

Key Words: Chronic endometritis, IVF, endometrial biopsy

a Centre for Reproductive Medicine, Dutch-Speaking Free University Brussels, Brussels, Belgium

b Department of Pathology, Dutch-Speaking Free University Brussels, Brussels, Belgium

c Department of Reproductive Medicine and Gynecology, University Medical Center, Utrecht, The Netherlands

Reprint requests: Human Mousavi Fatemi, M.D., Ph.D., V.U.B/C.R.G., Laarbeeklaan 101, 1090 Brussels, Belgium (FAX: +32-2-4776333).

H.M.F. has nothing to disclose. B.P-T. has nothing to disclose. L.A. has nothing to disclose. C.B. has nothing to disclose. B.F. has nothing to disclose. P.D. has nothing to disclose.

PII: S0015-0282(08)04741-9

doi:10.1016/j.fertnstert.2008.12.050

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