Fertility and Sterility
Volume 93, Issue 2 , Pages 586-591 , 15 January 2010

A prospective, randomized, double-blinded study of assisted hatching in women younger than 38 years undergoing in vitro fertilization

Received 26 October 2008 ,Revised 24 December 2008 ,Accepted 19 January 2009.

References 

  1. Cohen J. Assisted hatching of human embryos. J. In Vitro Fert Embryo Transf. 1991;8:179–190
  2. Seif MMW, Edi-Osagie EC, Farquhar C, Hooper L, Blake D, McGinlay P. Assisted hatching on assisted conception (IVF & ICSI). Cochrane Database Syst Rev. 2006;CD001894
  3. Alikani M, Cekleniak NA, Walters E, Cohen J. Monozygotic twinning following assisted conception: an analysis of 81 consecutive cases. Hum Reprod. 2003;18:1937–1943
  4. da Costa AL, Abdelmassih S, de Oliveira FG, Abdelmassih V, Abdelmassih R, Nagy ZP, et al. Monozygotic twins and transfer at the blastocyst stage after ICSI. Hum Reprod. 2001;16:333–336
  5. Hurst BS, Tucker KE, Awoniyi CA, Schlaff WD. Assisted hatching does not enhance IVF success in good-prognosis patients. J Assist Reprod Genet. 1998;15:62–64
  6. Schieve LA, Meikle SF, Peterson HB, Jeng G, Burnett NM, Wilcox LS. Does assisted hatching pose a risk for monozygotic twinning in pregnancies conceived through in vitro fertilization?. Fertil Steril. 2000;74:288–294
  7. The role of assisted hatching in in vitro fertilization: a review of the literature. A Committee opinion. Fertil Steril. 2006;86:S124–S126
  8. Mansour RT, Rhodes CA, Aboulghar MA, Serour GI, Kamal A. Transfer of zona-free embryos improves outcome in poor prognosis patients: a prospective randomized controlled study. Hum Reprod. 2000;15:1061–1064
  9. Fleiss JL. Statistical methods for rates and proportions. 2nd ed.. Hoboken, Wiley-Interscience; 2000;
  10. Sagoskin AW, Levy MJ, Tucker MJ, Richter KS, Widra EA. Laser assisted hatching in good prognosis patients undergoing in vitro fertilization-embryo transfer: a randomized controlled trial. Fertil Steril. 2007;87:283–287
  11. Olson CK, Keppler-Noreuil KM, Romitti PA, Budelier WT, Ryan G, Sparks AE, et al. In vitro fertilization is associated with an increase in major birth defects. Fertil Steril. 2005;84:1308–1315
  12. Loret De Mola JR, Garside WT, Bucci J, Tureck RW, Heyner S. Analysis of the human zona pellucida during culture: correlation with diagnosis and the preovulatory hormonal environment. J Assist Reprod Genet. 1997;14:332–336
  13. Sun YP, Xu Y, Cao T, Su YC, Guo YH. Zona pellucida thickness and clinical pregnancy outcome following in vitro fertilization. Int J Gynecol Obstet. 2005;89:258–262
  14. Lanzendorf SE, Ratts VS, Moley KH, Goldstein JS, Dahan MH, Odem RR. A randomized, prospective study comparing laser-assisted hatching and assisted hatching using acidified medium. Fertil Steril. 2007;87:1450–1457

 Supported by Barnes-Jewish Hospital Foundation.

 A.R.H. has nothing to disclose. S.E.L. has nothing to disclose. E.S.J. has nothing to disclose. A.S.C. has nothing to disclose. V.S.R. has nothing to disclose. R.R.O. has nothing to disclose.

PII: S0015-0282(09)00237-4

doi: 10.1016/j.fertnstert.2009.01.116

Fertility and Sterility
Volume 93, Issue 2 , Pages 586-591 , 15 January 2010

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