Fertility and Sterility
Volume 93, Issue 7 , Pages 2303-2310 , 1 May 2010

Metformin effects on ovarian ultrasound appearance and steroidogenic function in normal-weight normoinsulinemic women with polycystic ovary syndrome: a randomized double-blind placebo-controlled clinical trial

  • Daniela Romualdi, M.D.

      Affiliations

    • Department of Obstetrics and Gynecology, Università Cattolica del Sacro Cuore, Rome, Italy
  • ,
  • Maddalena Giuliani, M.D.

      Affiliations

    • Department of Obstetrics and Gynecology, Università Cattolica del Sacro Cuore, Rome, Italy
  • ,
  • Francesca Cristello, M.D.

      Affiliations

    • Department of Obstetrics and Gynecology, Università Cattolica del Sacro Cuore, Rome, Italy
  • ,
  • Anna Maria Fulghesu, M.D.

      Affiliations

    • Division of Gynecology, Obstetrics, and Pathophysiology of Human Reproduction, Department of Surgery, Maternal-Fetal Medicine, and Imaging, University of Cagliari, Cagliari, Italy
  • ,
  • Luigi Selvaggi, M.D.

      Affiliations

    • Department of Obstetrics and Gynecology, Università Cattolica del Sacro Cuore, Rome, Italy
  • ,
  • Antonio Lanzone, M.D.

      Affiliations

    • Department of Obstetrics and Gynecology, Università Cattolica del Sacro Cuore, Rome, Italy
    • “Oasi” Institute for Research, Troina, Italy
  • ,
  • Maurizio Guido, M.D., Ph.D.

      Affiliations

    • Department of Obstetrics and Gynecology, Università Cattolica del Sacro Cuore, Rome, Italy
    • Corresponding Author InformationReprint requests: Maurizio Guido, M.D., Ph.D., Department of Obstetrics and Gynaecology, Università Cattolica del Sacro Cuore, L.go Agostino Gemelli, 8, 00168 Rome, Italy (FAX: +39-06-3057794).

Received 1 October 2008 ,Revised 14 January 2009 ,Accepted 19 January 2009.

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 D.R. has nothing to disclose. M.G. has nothing to disclose. F.C. has nothing to disclose. A.M.F. has nothing to disclose. L.S. has nothing to disclose. A.L. has nothing to disclose. M.G. has nothing to disclose.

 Supported by a grant from the Ministry of Public Health for “La prevenzione dell'handicap mentale,” Istituto di Ricovero e Cura a Carattere Scientifico Troina and by a grant from the Ministry of Education, Univerities, and Research, 2005.

PII: S0015-0282(09)00239-8

doi: 10.1016/j.fertnstert.2009.01.114

Fertility and Sterility
Volume 93, Issue 7 , Pages 2303-2310 , 1 May 2010