Fertility and Sterility
Volume 92, Issue 3 , Pages 1009-1011 , September 2009

Intrauterine insemination with or without mild ovarian stimulation in couples with male subfertility due to oligo/astheno- and/or teratozoospermia or antisperm antibodies: a prospective cross-over trial

  • Felice Francavilla, M.D.

      Affiliations

    • Andrologic Unit, Department of Internal Medicine, University of L'Aquila, L'Aquila, Italy
    • Corresponding Author InformationReprint requests: Prof. Felice Francavilla, M.D., Department of Internal Medicine, University of L'Aquila, Blocco 11, Coppito, 67100, Coppito, L'Aquila, Italy (FAX: +39 0862 368342).
    • ,
  • Filomena Sciarretta, M.D.

      Affiliations

    • Andrologic Unit, Department of Internal Medicine, University of L'Aquila, L'Aquila, Italy
    • ,
  • Sara Sorgentone, M.D.

      Affiliations

    • Andrologic Unit, Department of Internal Medicine, University of L'Aquila, L'Aquila, Italy
    • ,
  • Stefano Necozione, M.D.

      Affiliations

    • Epidemiology, Department of Internal Medicine, University of L'Aquila, L'Aquila, Italy
    • ,
  • Riccardo Santucci, Ph.D.

      Affiliations

    • Andrologic Unit, Department of Internal Medicine, University of L'Aquila, L'Aquila, Italy
    • ,
  • Arcangelo Barbonetti, M.D.

      Affiliations

    • Andrologic Unit, Department of Internal Medicine, University of L'Aquila, L'Aquila, Italy
    • ,
  • Sandro Francavilla, M.D.

      Affiliations

    • Andrologic Unit, Department of Internal Medicine, University of L'Aquila, L'Aquila, Italy

Received 23 September 2008 ,Revised 13 January 2009 ,Accepted 19 January 2009.

References 

  1. Bensdorp AJ, Cohlen BJ, Heineman MJ, Vandekerckhove P. Intra-uterine insemination for male subfertility. Cochrane Database Syst Rev. 2007 Oct 17;(4):CD000360
  2. Francavilla F, Santucci R, Barbonetti A, Francavilla S. Naturally-occurring antisperm antibodies in men: interference with fertility and clinical implications. An update. Front Biosci. 2007;12:d2890–d2911
  3. Min JK, Breheny SA, Mac Lachlan V, Healy DV. What is the most relevant standard of success in assisted reproduction? The singleton, term gestation, live birth rate per cycle initiated: the BESST endpoint for assisted reproduction. Hum Reprod. 2004;19:3–7
  4. Fauser BC, Devroey P, Macklon NS. Multiple birth resulting from ovarian stimulation for subfertility treatment. Lancet. 2005;365:1807–1816
  5. NICE (National Institute for Clinical Excellence) Fertility . Assessment and treatment for people with fertility problems. Clinical guideline. London: RCOG Press; 2004;74–80
  6. World Health Organization (WHO) . WHO laboratory manual for the examination of human semen and semen–cervical mucus interaction. 4th ed.. London: Cambridge University Press; 1999;4–33
  7. Kalbfleisch J, Prentice RL. The statistical analysis of failure time data. New York: Wiley; 1980;
  8. Cohlen BJ, te Velde ER, van Kooij RJ, Looman CW, Habbema JD. Controlled ovarian hyperstimulation and intrauterine insemination for treating male subfertility: a controlled study. Hum Reprod. 1998;13:1553–1558
  9. Collins JA, Burrows EA, Wilan AR. The prognosis for live birth among untreated infertile couples. Fertil Steril. 1995;64:22–28
  10. Van Waart J, Kruger TF, Lombard CJ, Ombelet W. Predictive value of normal sperm morphology in intrauterine insemination (IUI): a structured literature review. Hum Reprod Update. 2001;7:495–500
  11. Lombardo F, Gandini L, Dondero F, Lenzi A. Antisperm immunity in natural and assisted reproduction. Hum Reprod Update. 2001;7:450–456
  12. Steures P, van der Steeg JW, Verhoeve HR, van Dop PA, Hompes PG, Bossuyt PM, et al. Does ovarian hyperstimulation in intrauterine insemination for cervical factor subfertility improve pregnancy rates?. Hum Reprod. 2004;19:2263–2266

 F.F. has nothing to disclose. F.S. has nothing to disclose. S.S. has nothing to disclose. S.N. has nothing to disclose. R.S. has nothing to disclose. A.B. has nothing to disclose. S.F. has nothing to disclose.

PII: S0015-0282(09)00241-6

doi: 10.1016/j.fertnstert.2009.01.112

Fertility and Sterility
Volume 92, Issue 3 , Pages 1009-1011 , September 2009

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