Fertility and Sterility
Volume 93, Issue 2 , Pages 480-485 , 15 January 2010

Hepatitis B infection and outcomes of in vitro fertilization and embryo transfer treatment

  • Po Mui Lam, M.D.

      Affiliations

    • Department of Obstetrics and Gynecology, Prince of Wales Hospital, Shatin, New Territories, Hong Kong, People's Republic of China
    • Corresponding Author InformationReprint requests: Po Mui Lam, M.D., Department of Obstetrics & Gynecology, Prince of Wales Hospital, Shatin, New Territories, Hong Kong S.A.R., China (FAX: 852-2636-0008).
  • ,
  • Sik Hung Suen, M.R.C.O.G.

      Affiliations

    • Department of Obstetrics and Gynecology, Prince of Wales Hospital, Shatin, New Territories, Hong Kong, People's Republic of China
  • ,
  • Terence Tzu Lao, M.D.

      Affiliations

    • The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, People's Republic of China
  • ,
  • Lai Ping Cheung, M.R.C.O.G.

      Affiliations

    • Department of Obstetrics and Gynecology, Prince of Wales Hospital, Shatin, New Territories, Hong Kong, People's Republic of China
  • ,
  • Tak Yeung Leung, M.D.

      Affiliations

    • Department of Obstetrics and Gynecology, Prince of Wales Hospital, Shatin, New Territories, Hong Kong, People's Republic of China
  • ,
  • Christopher Haines, M.D.

      Affiliations

    • The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, People's Republic of China

Received 1 December 2008 ,Revised 14 January 2009 ,Accepted 24 January 2009.

References 

  1. Ocama P, Opio C, Lee W. Hepatitis B virus infection: current status. Am J Med. 2005;118:1413
  2. Van den E. Investigation and treatment of infertile couples: ESHRE guidelines for good clinical and laboratory practice. European Society of Human Reproduction and Embryology. Hum Reprod. 1995;10:1246–1271
  3. Qian W, Tan Y, Chen Y, Peng Y, Li Z, Lu G, et al. Rapid quantification of semen hepatitis B virus DNA by real-time polymerase chain reaction. World J Gastroenterol. 2005;11:5385–5389
  4. Huang J, Huang T, Qiu H, Fang X, Zhuang T, Liu H, et al. Effects of hepatitis B virus infection on human sperm chromosomes. World J Gastroenterol. 2003;9:736–740
  5. Moretti E, Federico M, Giannerini V, Collodel G. Sperm ultrastructure and meiotic segregation in a group of patients with chronic hepatitis B and C. Andrologia. 2008;40:286–291
  6. Ye F, Yue Y, Li S, Chen T, Bai G, Liu M, et al. Presence of HBsAg, HBcAg, and HBV DNA in ovary and ovum of the patients with chronic hepatitis B virus infection. Am J Obstet Gynecol. 2006;194:387–392
  7. Pirwany I, Phillips S, Kelly S, Buckett W, Tan S. Reproductive performance of couples discordant for hepatitis B and C following IVF treatment. J Assist Reprod Genet. 2004;21:157–161
  8. Chen C, Wang L, Yu M. Epidemiology of hepatitis B virus infection in the Asia–Pacific region. J Gastroenterol Hepatol. 2000;15(Suppl):E3–E6
  9. Ma J, Bauman A. Obstetric profiles and pregnancy outcomes of immigrant women in New South Wales. 1990–1992. Aust N Z J Obstet Gynaecol. 1996;36:119–125
  10. Kawsar M, Goh B. Hepatitis B virus infection among Chinese residents in the United Kingdom. Sex Transm Infect. 2002;78:166–168
  11. Casagrande J, Pike M, Smith P. Statistical methods for rates and proportions: an improved approximate formula for calculating sample sizes for comparing two binomial distributions. In:  Fleiss JL editors. Biometrics. 2nd ed.. New York: Wiley; 1981;p. 483–486
  12. Levy R, Tardy JC, Bourlet T, Cordonier H, Mion F, Lornage J, et al. Transmission risk of hepatitis C virus in assisted reproductive techniques. Hum Reprod. 2000;15:810–816
  13. Zhao E, Chen S, Sun L, Yin M, Xiong X, Song J, et al. Influence of chronic HBV infection in the husband on the outcome of IVF-ET treatment. Nan Fang Yi Ke Da Xue Xue Bao. 2007;27:1827–1829
  14. Ogunkunle M, Oni A, Odaibo G, Olaleye O. Hepatitis B surface antigen (HbsAg) in blood and genital secretions of patients with sexually transmitted diseases in Ibadan, Nigeria. West Afr J Med. 2005;24:206–208
  15. Huang J, Huang T, Qiu H, Fang X, Zhuang T, Qiu J. Studies on the integration of hepatitis B virus DNA sequence in human sperm chromosomes. Asian J Androl. 2002;4:209–212
  16. Wang S, Peng G, Li M, Xiao H, Jiang P, Zeng N, et al. Identification of hepatitis B virus vertical transmission from father to fetus by direct sequencing. Southeast Asian J Trop Med Public Health. 2003;34:106–113

 P.M.L. has nothing to disclose. S.H.S. has nothing to disclose. T.T.H.L. has nothing to disclose. L.P.C. has nothing to disclose. T.Y.L. has nothing to disclose. C.H. has nothing to disclose.

PII: S0015-0282(09)00265-9

doi: 10.1016/j.fertnstert.2009.01.137

Fertility and Sterility
Volume 93, Issue 2 , Pages 480-485 , 15 January 2010