Fertility and Sterility
Volume 94, Issue 2 , Pages 450-452 , July 2010

Interleukin-8 serum levels do not correlate with pelvic pain in patients with ovarian endometriomas

  • Manuel García Manero, M.D.

      Affiliations

    • Corresponding Author InformationReprint requests: Manuel García Manero, M.D., Department of Obstetrics and Gynecology, School of Medicine, University of Navarra, Pamplona, Spain 31008.
    • ,
  • Juan Luis Alcazar, M.D.

Received 23 October 2008 ,Revised 17 March 2009 ,Accepted 19 March 2009.

References 

  1. Donnez J, Smoes P, Gillerot S, Casanas-Roux F, Nisolle M. Vascular endothelial growth factor (VEGF) in endometriosis. Hum Reprod. 1998;13:1686–1690
  2. Matsuzaki S, Canis M, Darcha C, Dechelotte P, Pouly JL, Bruhat MA. Angiogenesis in endometriosis. Gynecol Obstet Invest. 1998;46:111–115
  3. McLaren J, Prentice A, Charnock-Jones DS, Millican SA, Müller KH, Sharkey AM, et al. Vascular endothelial growth factor (VEGF) concentrations are elevated in peritoneal fluid of women with endometriosis. Hum Reprod. 1996;11:220–223
  4. Taylor RN, Lebovic DI, Mueller MD. Angiogenic factors in endometriosis. Ann N Y Acad Sci. 2002;955:89–100
  5. Ferriani RA, Charnock-Jones DS, Prentice A, Thomas EJ, Smith SK. Immunohistochemical localization of acidic and basic fibroblast growth factors in normal human endometrium and endometriosis and the detection of their mRNA by polymerase chain reaction. Hum Reprod. 1993;8:11–16
  6. Fujimoto J, Sakaguchi H, Hirose R, Tamaya T. Expression of platelet-derived endothelial cell growth factor (PD-ECGF) related to angiogenesis in ovarian endometriomata. J Clin Endocrinol Metab. 1999;84:359–362
  7. Goteri G, Lucarini G, Filosa A, Pierantoni A, Montik N, Biagini G, et al. Immunohistochemical analysis of vascular endothelial growth factor cellular expression in ovarian endometriomata. Fertil Steril. 2004;81:1528–1533
  8. Vercellini P. Endometriosis: what a pain it is. Semin Reprod Endocrinol. 1997;15:251–261
  9. Alcazar JL. Transvaginal colour Doppler in patients with ovarian endometriomas and pelvic pain. Hum Reprod. 2001;16:2672–2675
  10. Koch AE, Polverini PJ, Kunkel SL, Harlow LA, DiPietro LA, Elner VM, et al. Interleukin-8 as a macrophage-derived mediator of angiogenesis. Science. 1992;258:1798–1801
  11. Iwabe T, Harada T, Tsudo T, Tanikawa M, Onohara Y, Terakawa N. Pathogenetic significance of increased levels of interleukin-8 in the peritoneal fluid of patients with endometriosis. Fertil Steril. 1998;69:924–930
  12. García-Manero M, Alcazar JL, Toledo G. Vascular endothelial growth factor (VEGF) and ovarian endometriosis: correlation between VEGF serum levels, VEGF cellular expression, and pelvic pain. Fertil Steril. 2007;88:513–515
  13. Fasciani A, D'Ambrogio G, Bocci G, Monti M, Genazzi AR, Artini PG. High concentrations of the vascular endothelial growth factor and interleukin-8 in ovarian endometriomata. Mol Hum Reprod. 2000;6:50–54
  14. Price DD, McGrath PA, Rafii A, Buckingham B. The validation of visual analogue scales as ratio scale measures for chronic and experimental pain. Pain. 1983;17:45–56
  15. Revised American Fertility Society classification of endometriosis: 1985. Fertil Steril. 1985;43:351–352
  16. Gagne D, Pagé M, Robitaille G, Hugo P, Gosselin D. Levels of vascular endothelial growth factor (VEGF) in serum of patients with endometriosis. Hum Reprod. 2003;18:1674–1680
  17. Nisolle M, Donnez J. Peritoneal endometriosis, ovarian endometriosis, and adenomyotic nodules of the rectovaginal septum are three different entities. Fertil Steril. 1997;68:585–596
  18. Healy DL, Rogers PA, Hii L, Wingfield M. Angiogenesis: a new theory for endometriosis. Hum Reprod Update. 1998;4:736–740
  19. Matalliotakis IM, Goumenou AG, Koumantakis GE, Neonaki MA, Koumantakis EE, Dionyssopoulou E, et al. Serum concentrations of growth factors in women with and without endometriosis: the action of anti-endometriosis medicines. Int Immunopharmacol. 2003;3:81–89
  20. Pellicer A, Albert C, Mercader A, Bonilla-Musoles F, Remohí J, Simón C. The follicular and endocrine environment in women with endometriosis: local and systemic cytokine production. Fertil Steril. 1998;70:425–431
  21. Ohata Y, Harada T, Miyakoda H, Taniguchi F, Iwabe T, Terakawa N. Serum interleukin-8 levels are elevated in patients with ovarian endometrioma. Fertil Steril. 2008;90:994–999

 M.G.M. has nothing to disclose. J.L.A. has nothing to disclose.

PII: S0015-0282(09)00744-4

doi: 10.1016/j.fertnstert.2009.03.074

Fertility and Sterility
Volume 94, Issue 2 , Pages 450-452 , July 2010

Article Tools