Genetic variation in the vitamin D receptor and polycystic ovary syndrome risk
Received 29 January 2009; received in revised form 19 April 2009; accepted 5 May 2009. published online 08 June 2009.
The possible association of vitamin D receptor gene FokI, BsmI, ApaI, and TaqI polymorphisms with polycystic ovary syndrome (PCOS) risk, and their influence on insulin resistance and serum levels of insulin in the women with PCOS was examined. The findings of the present study indicate that genetic variation in the vitamin D receptor may affect PCOS development as well as insulin resistance in women with PCOS.
Department of Genetics, Reproductive Biomedicine Research Center, Royan Institute, Tehran, Iran
Reprint requests: Touraj Mahmoudi, M.Sc., Department of Genetics, Reproductive Biomedicine Research Center, Royan Institute, 5 Hafez Street, BaniHashem Square,19395-4644, Tehran, Iran (FAX: +982122305236).
T.M. has nothing to disclose.
Supported by a grant from the Royan Institute, Tehran, Iran.
ABSTRACT