Fertility and Sterility
Volume 93, Issue 1 , Pages 286-288, 1 January 2010

A short period of ejaculatory abstinence before intrauterine insemination is associated with higher pregnancy rates

  • Paul B. Marshburn, M.D.

      Affiliations

    • Division of Reproductive Endocrinology and Infertility, Carolinas Medical Center, Charlotte
    • Department of Obstetrics and Gynecology, Carolinas Medical Center, Charlotte
    • Corresponding Author InformationReprint requests: Paul B. Marshburn, M.D., Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Carolinas Medical Center, 1000 Blythe Blvd., Charlotte, North Carolina 28232-2861 (TEL: 704-355-3153; FAX: 704-355-1941).
    • ,
  • Mark Alanis, M.D.

      Affiliations

    • Department of Obstetrics and Gynecology, Medical University of South Carolina, Charleston, South Carolina
    • ,
  • Michelle L. Matthews, M.D.

      Affiliations

    • Division of Reproductive Endocrinology and Infertility, Carolinas Medical Center, Charlotte
    • Department of Obstetrics and Gynecology, Carolinas Medical Center, Charlotte
    • ,
  • Rebecca Usadi, M.D.

      Affiliations

    • Division of Reproductive Endocrinology and Infertility, Carolinas Medical Center, Charlotte
    • Department of Obstetrics and Gynecology, Carolinas Medical Center, Charlotte
    • ,
  • Margaret H. Papadakis, Ph.D.

      Affiliations

    • Division of Reproductive Endocrinology and Infertility, Carolinas Medical Center, Charlotte
    • Department of Obstetrics and Gynecology, Carolinas Medical Center, Charlotte
    • ,
  • Susan Kullstam, M.S.

      Affiliations

    • Department of Obstetrics and Gynecology, Carolinas Medical Center, Charlotte
    • ,
  • Bradley S. Hurst, M.D.

      Affiliations

    • Division of Reproductive Endocrinology and Infertility, Carolinas Medical Center, Charlotte
    • Department of Obstetrics and Gynecology, Carolinas Medical Center, Charlotte

Received 20 March 2009; received in revised form 27 June 2009; accepted 8 July 2009. published online 03 September 2009.

An ejaculatory abstinence period of ≤2 days before IUI produced the highest pregnancy rates per cycle compared with longer intervals of ejaculatory abstinence. This higher conception rate occurred despite a lower total number of motile spermatozoa inseminated.

Key Words: Intrauterine insemination, infertility, ovulation induction, ejaculatory abstinence, semen analysis, sperm parameters

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 Supported by the Health Services Foundation, Carolinas Medical Center, Charlotte, North Carolina.

 P.B.M. has nothing to disclose. M.A. has nothing to disclose. M.L.M. has nothing to disclose. R.U. has nothing to disclose. M.H.P. has nothing to disclose. S.K. has nothing to disclose. B.S.H. has nothing to disclose.

PII: S0015-0282(09)02462-5

doi:10.1016/j.fertnstert.2009.07.972

Fertility and Sterility
Volume 93, Issue 1 , Pages 286-288, 1 January 2010

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