Fertility and Sterility
Volume 93, Issue 1 , Pages 289-292, 1 January 2010

Cytogenetic analysis of early nonviable pregnancies after assisted reproduction treatment

  • M. Carmen Martínez, M.Sc.

      Affiliations

    • Instituto Valenciano de Infertilidad in Murcia (IVI-Murcia), Murcia, Spain
    • Corresponding Author InformationReprint requests: M. Carmen Martínez, M.Sc., IVI-Murcia, C/Navegante Macías del Poyo no. 5, 30007, Murcia, Spain (FAX: 34-968-23-40-63).
    • ,
  • Carmen Méndez, B.Sc.

      Affiliations

    • Instituto Valenciano de Infertilidad in Murcia (IVI-Murcia), Murcia, Spain
    • ,
  • Jaime Ferro, M.D.

      Affiliations

    • Instituto Valenciano de Infertilidad, Valencia, Spain
    • ,
  • Maria Nicolás, M.D.

      Affiliations

    • Instituto Valenciano de Infertilidad in Murcia (IVI-Murcia), Murcia, Spain
    • ,
  • Vicente Serra, M.D., Ph.D.

      Affiliations

    • Instituto Valenciano de Infertilidad, Valencia, Spain
    • ,
  • Jose Landeras, M.D.

      Affiliations

    • Instituto Valenciano de Infertilidad in Murcia (IVI-Murcia), Murcia, Spain

Received 10 February 2009; received in revised form 26 June 2009; accepted 14 July 2009. published online 11 September 2009.

In our series, a very high prevalence of chromosomal abnormalities was observed in spontaneous miscarriages, irrespective of how pregnancy was achieved, by assisted reproductive technology (ART) or natural conception. This high prevalence was equally represented in both groups, with no statistical difference in type of chromosomal abnormalities or in total frequency; however, the incidence of monosomy X is increased and the polyploidies are decreased in abortus after intracytoplasmic sperm injection (ICSI) when it is compared with miscarriages after spontaneous gestations.

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 M.C.M. has nothing to disclose. C.M. has nothing to disclose. J.F. has nothing to disclose. M.N. has nothing to disclose. V.S. has nothing to disclose. J.L. has nothing to disclose.

PII: S0015-0282(09)02485-6

doi:10.1016/j.fertnstert.2009.07.989

Fertility and Sterility
Volume 93, Issue 1 , Pages 289-292, 1 January 2010

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