Cytogenetic analysis of early nonviable pregnancies after assisted reproduction treatment
Received 10 February 2009; received in revised form 26 June 2009; accepted 14 July 2009. published online 11 September 2009.
In our series, a very high prevalence of chromosomal abnormalities was observed in spontaneous miscarriages, irrespective of how pregnancy was achieved, by assisted reproductive technology (ART) or natural conception. This high prevalence was equally represented in both groups, with no statistical difference in type of chromosomal abnormalities or in total frequency; however, the incidence of monosomy X is increased and the polyploidies are decreased in abortus after intracytoplasmic sperm injection (ICSI) when it is compared with miscarriages after spontaneous gestations.
aInstituto Valenciano de Infertilidad in Murcia (IVI-Murcia), Murcia, Spain
bInstituto Valenciano de Infertilidad, Valencia, Spain
Reprint requests: M. Carmen Martínez, M.Sc., IVI-Murcia, C/Navegante Macías del Poyo no. 5, 30007, Murcia, Spain (FAX: 34-968-23-40-63).
M.C.M. has nothing to disclose. C.M. has nothing to disclose. J.F. has nothing to disclose. M.N. has nothing to disclose. V.S. has nothing to disclose. J.L. has nothing to disclose.
ABSTRACT