Fertility and Sterility
Volume 93, Issue 3 , Pages 1020-1023 , February 2010

HIV-1 or hepatitis C chronic infection in serodiscordant infertile couples has no impact on infertility treatment outcome

  • Nadia Prisant, M.D.

      Affiliations

    • UF de Biologie de la Reproduction, Groupe Hospitalier Pitié Salpêtrière, Paris, France
    • ,
  • Roland Tubiana, M.D.

      Affiliations

    • Service de Maladies Infectieuses, Groupe Hospitalier Pitié Salpêtrière, Paris, France
    • ,
  • Gilles Lefebvre, M.D.

      Affiliations

    • Gynécologie-Obstétrique, Groupe Hospitalier Pitié Salpêtrière, Paris, France
    • ,
  • Pascal Lebray, M.D.

      Affiliations

    • Hépato-Gastro-Entérologie, Groupe Hospitalier Pitié Salpêtrière, Paris, France
    • ,
  • Anne Genevieve Marcelin, Ph.D.

      Affiliations

    • Service de Virologie, Groupe Hospitalier Pitié Salpêtrière, Paris, France
    • ,
  • Vincent Thibault, Pharm.D.

      Affiliations

    • Service de Virologie, Groupe Hospitalier Pitié Salpêtrière, Paris, France
    • ,
  • Ouriel Rosenblum, Ph.D.

      Affiliations

    • Psychiatrie de l'Enfant et de l'Adolescent, Groupe Hospitalier Pitié Salpêtrière, Paris, France
    • ,
  • Manuela Bonmarchand, M.D.

      Affiliations

    • Service de Maladies Infectieuses, Groupe Hospitalier Pitié Salpêtrière, Paris, France
    • ,
  • Danielle Vauthier-Brouzes, M.D.

      Affiliations

    • Gynécologie-Obstétrique, Groupe Hospitalier Pitié Salpêtrière, Paris, France
    • ,
  • Jean Louis Golmard, Ph.D.

      Affiliations

    • Unité de Biostatistique et Information Médicale, Groupe Hospitalier Pitié Salpêtrière, Paris, France
    • ,
  • Christine Katlama, Ph.D.

      Affiliations

    • Service de Maladies Infectieuses, Groupe Hospitalier Pitié Salpêtrière, Paris, France
    • ,
  • Catherine Poirot, Ph.D.

      Affiliations

    • UF de Biologie de la Reproduction, Groupe Hospitalier Pitié Salpêtrière, Paris, France
    • Corresponding Author InformationReprint requests: Catherine Poirot, Ph.D., UF de Biologie de la Reproduction, Groupe Hospitalier Pitié-Salpêtrière, Bâtiment 85, entresol, 83, Bld de l'Hôpital, 75013 Paris, France (FAX: 33 (0)1 42 17 78 89).

Received 22 October 2008 ,Revised 4 July 2009 ,Accepted 24 July 2009.

References 

  1. Journal Officiel de la République Française Decree Concerning Assisted Reproductive Treatment of Patients with Viral Risks. May 15, 2001.
  2. Hammoud I, Vialard F, Casasnovas P, Lefebvre G, Vauthier-Brouzes D, Poirot C. How viable are zygotes in which the PN are still intact at 25 hours? Impact on the choice of embryo for transfer. Fertil Steril. 2008;3:551–556
  3. Ohl J, Partisani M, Wittemer C, Schmitt MP, Cranz C, Stoll-Keller F, et al. Assisted reproduction techniques for HIV serodiscordant couples: 18 months of experience. Hum Reprod. 2003;18:1244–1249
  4. Ohl J, Partisani M, Wittemer C, Lang JM, Viville S, Favre R. Encouraging results despite complexity of multidisciplinary care of HIV-infected women using assisted reproduction techniques. Hum Reprod. 2005;20:3136–3140
  5. Terriou P, Auquier P, Chabert-Orsini V, Chinchole JM, Cravello L, Giorgetti C, et al. Outcome of ICSI in HIV-1-infected women. Hum Reprod. 2005;20:102838–102843
  6. Baccetti B, Benedetto A, Burrini AG, Collodel G, Ceccarini EC, Crisa N, et al. HIV-particles in spermatozoa of patients with AIDS and their transfer into the oocyte. J Cell Biol. 1994;4:903–914
  7. Baccetti B, Benedetto A, Collodel G, Crisá N, di Caro A, Garbuglia AR, et al. Failure of HIV-1 to infect human oocytes directly. J Acquir Immune Defic Syndr. 1999;5:355–361
  8. Wilson JD, Dunham RJ, Balen AH. HIV protease inhibitors, the lipodystrophy syndrome and polycystic ovary syndrome—is there a link?. Sex Transm Infect. 1999;4:268–269
  9. Hadigan C, Corcoran C, Piecuch S, Rodriguez W, Grinspoon S. Hyperandrogenemia in human immunodeficiency virus-infected women with the lipodystrophy syndrome. J Clin Endocrinol Metab. 2000;10:3544–3550
  10. Martinet V, Manigart Y, Rozenberg S, Becker B, Gerard M, Delvigne A. Ovarian response to stimulation of HIV-positive patients during IVF treatment: a matched, controlled study. Hum Reprod. 2006;26:1–6
  11. Seifer DB, Golub ET, Lambert-Messerlian G, Springer G, Holman S, Moxley M, et al. Biologic markers of ovarian reserve and reproductive aging: application in a cohort study of HIV infection in women. Fertil Steril. 2007;6:1645–1652
  12. Barreto-Melo MA, Meseguer M, Bellver J, Remohí J, Pellicer A, Garrido N. Human immunodeficiency type-1 virus (HIV-1) infection in serodiscordant couples (SDCs) does not have an impact on embryo quality or intracytoplasmic sperm injection (ICSI) outcome. Fertil Steril. 2008;1:141–150
  13. Manigart Y, Rozenberg S, Barlow P, Gerard M, Bertrand E, Delvigne A. ART outcome in HIV-infected patients. Hum Reprod. 2006;11:2935–2940
  14. Savasi V, Ferrazzi E, Lanzani C, Oneta M, Parrilla B, Persico T. Safety of sperm washing and ART outcome in 741 HIV-1-serodiscordant couples. Hum Reprod. 2007;3:772–777
  15. López S, Coll O, Durban M, Hernàndez S, Vidal R, Suy A, et al. Mitochondrial DNA depletion in oocytes of HIV-infected antiretroviral-treated infertile women. Antivir Ther. 2008;13:833–838
  16. Dulioust E, Du AL, Costagliola D, Guibert J, Kunstmann JM, Heard I, et al. Semen alterations in HIV-1 infected men. Hum Reprod. 2002;17:2112–2118
  17. Englert Y, Moens E, Vannin A, Liesnard C, Emiliani S, Delbaere A, et al. Impaired ovarian stimulation during in vitro fertilization in women who are seropositive for hepatitis C virus and seronegative for human immunodeficiency virus. Fertil Steril. 2007;3:607–611
  18. Pirwany IR, Phillips S, Kelly S, Buckett W, Lin Tan S. Reproductive performance of couples discordant for hepatitis B and C following IVF treatment. J Assist Reprod Genet. 2004;5:157–161
  19. Levent G, Ali A, Ahmet A, Can Polat E, Aytaç Ç Ayşe E, et al. Oxidative stress and antioxidant defense in patients with chronic hepatitis C patients before and after pegylated interferon alfa-2b plus ribavirin therapy. J Transl Med. 2006;4:25–30
  20. Journal Officiel de la République Française Decree Concerning Assisted Reproductive Treatment of Patients with Viral Risks. May 23, 2008.
  21. Mowat NAG, Edwards CRW, Fisher R, McNeilly AS, Green JRB, Dawson AM. Hypothalamic–pituitary–gonadal function in men with cirrhosis of the liver. Gut. 1976;17:345–350

 N.P. has nothing to disclose. R.T. has nothing to disclose. G.L. has nothing to disclose. P.L. has nothing to disclose. A.G.M. has nothing to disclose. V.T. has nothing to disclose. O.R. has nothing to disclsoe. M.B. has nothing to disclose. D.V.-B. has nothing to disclose. T.L.B. has nothing to disclose. C.K. has nothing to disclose. C.P. has nothing to disclose.

PII: S0015-0282(09)03453-0

doi: 10.1016/j.fertnstert.2009.07.1663

Fertility and Sterility
Volume 93, Issue 3 , Pages 1020-1023 , February 2010

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