Fertility and Sterility
Volume 93, Issue 3 , Pages 1016-1019 , February 2010

Improvement in quality-of-life questionnaire measures in obese adolescent females with polycystic ovary syndrome treated with lifestyle changes and oral contraceptives, with or without metformin

Presented at the annual American Society of Reproductive Medicine meeting in San Francisco, CA, October 17, 2008.

Received 17 January 2009 ,Revised 7 July 2009 ,Accepted 2 August 2009.

References 

  1. Carmina EM, Azziz R. Diagnosis, phenotype, and prevalence of polycystic ovary syndrome. Fertil Steril. 2006;86:1:S7–8
  2. Franks S. Medical progress: polycystic ovary syndrome. N Engl J Med. 1995;333(13):853–861
  3. Trivax BM, Azziz R. Diagnosis of polycystic ovary syndrome. Clin Obstet Gynecol. 2007;50:168–177
  4. Yen SSC. The polycystic ovary syndrome. Clin Endocrinol (Oxf.). 1980;12:177–208
  5. Trent M, Rich M, Austin BS, Gordon CM. Quality of life in adolescent girls with polycystic ovary syndrome. AMA. 2002;156(6):556–560
  6. Trent ME, Austin BS, Rich M, Gordon CM. Overweight status of adolescent girls with polycystic ovary syndrome: body mass index as mediator of quality of life. Ambulatory Pediatrics. 2005;5(2):107–111
  7. Trent ME, Rich M, Austin BS, Gordon CM. Fertility concerns and sexual behavior in adolescent girls with polycystic ovary syndrome implications for quality of life. J Ped and Adolesc Gyn. 2003;16(1):33–37
  8. Pekhlivanov B, Kolarov G, Kavurdzhikova S, Stoikov S. Determinants of health related quality of life in women with polycystic ovary syndrome. Akusherstvo I Ginkekologiia. 2006;45(7):29–34
  9. Hahn S, Benson S, Elsenbruch S, Pleger K, Tan S, Mann K, et al. Metformin treatment of polycystic ovary syndrome improves health-related quality of life, emotional distress and sexuality. Hum Reprod. 2006;10:1093
  10. Cronin L, Guyatt G, Griffith L, Wong E, Azziz R, Futterweit W, et al. Development of a health-related quality-of-life questionnaire (PCOSQ) for women with polycystic ovary syndrome (PCOS). J Clin Endo & Met. 1998;83(6):1976–1987
  11. Jones GL, Benes K, Clark TL, Denham R, Holder MG, Haynes TJ, et al. The polycystic ovary syndrome health related quality of life questionnaire (PCOSQ): a validation. Hum Reprod. 2004;9(2):371–377
  12. Hoeger KM. Obesity and lifestyle management in polycystic ovary syndrome. Clin Obst & Gyn. 2007;50(1):277–294
  13. Trent ME, Upadhya K. Effects of polycystic ovary syndrome on health-related quality of life 2008; www.cdc.gov/hrqol/index.com Expert Review Pharmacoeconomics Res.
  14. Hedley AA, Ogden CL, Johnson CL, Carroll MD, Curtin LR, Flegal KM. Prevalence of overweight and obesity among US children, adolescents, and adults, 1999–2002. JAMA. 2004;291(23):2847–2850
  15. Janssen OE, Hahn S, Tan S, Benson S, Elsenbruch S. mood and sexual function in polycystic ovary syndrome: acne. Semin Reprod Med. 2008;26:45–52

 M.H.-G. has nothing to disclose. K.D. has nothing to disclose. L.K. has nothing to disclose. D.G. has nothing to disclose. K.H. has nothing to disclose.

 Supported by National Institutes of Health grant K23 HD043881-01A1 (K.M.H.) and grant UL1 RR 024160 from the National Center for Research Resources to the University of Rochester, Rochester, New York.

PII: S0015-0282(09)03458-X

doi: 10.1016/j.fertnstert.2009.08.006

Fertility and Sterility
Volume 93, Issue 3 , Pages 1016-1019 , February 2010

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