Fertility and Sterility
Volume 93, Issue 4 , Pages 1362-1365, 1 March 2010

Different phenotypes of polycystic ovary syndrome by Rotterdam criteria are differently steroidogenic but similarly insulin resistant

Presented as a poster at the 62nd Annual Meeting, American Society for Reproductive Medicine, October 21–25, 2006, New Orleans, Louisiana.

  • Yong Wang, Ph.D.

      Affiliations

    • Medical School, Nanjing University, Nanjing, People's Republic of China
    • Department of Obstetrics and Gynecology, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin, People's Republic of China
    • ,
  • JunWei Qu, M.D.

      Affiliations

    • Medical School, Nanjing University, Nanjing, People's Republic of China
    • Department of Obstetrics and Gynecology, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin, People's Republic of China
    • ,
  • XiaoKe Wu, M.D., Ph.D.

      Affiliations

    • Department of Obstetrics and Gynecology, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin, People's Republic of China
    • Corresponding Author InformationReprint requests: Xiaoke Wu, M.D., Ph.D., Department of Obstetrics and Gynecology, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin, 150040 China (FAX: +86-451-8213-0094).
    web address
    • ,
  • LiHui Hou, M.D.

      Affiliations

    • Department of Obstetrics and Gynecology, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin, People's Republic of China
    • ,
  • Risto Erkkola, M.D., Ph.D.

      Affiliations

    • Department of Obstetrics and Gynecology, Turku University Central Hospital, Turku, Finland
    • ,
  • Yongyan Wang, M.D.

      Affiliations

    • Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Science, Beijing, People's Republic of China

Received 17 January 2009; received in revised form 30 June 2009; accepted 1 July 2009. published online 28 September 2009.

In traditional Chinese medicine, polycystic ovary syndrome (PCOS) is considered an anovulation disorder related to ovarian insulin resistance. The three phenotypes of PCOS, according to the Rotterdam criteria, are differently steroidogenic but similarly insulin resistant, suggesting a similar involvement of insulin resistance/hyperinsulinemia in different compartments of the PCOS ovary, namely, overactive theca and/or granulosa cells.

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 Y.W. has nothing to disclose. J.Q. has nothing to disclose. X.W. has nothing to disclose. L.H. has nothing to disclose. R.E. has nothing to disclose. Y.W. has nothing to disclose.

 Supported by the National Clinical Research Base of Gynecology in Chinese Medicine, and the Heilongjiang Province Foundation for Outstanding Youths (JC200804).

PII: S0015-0282(09)03476-1

doi:10.1016/j.fertnstert.2009.07.1678

Fertility and Sterility
Volume 93, Issue 4 , Pages 1362-1365, 1 March 2010

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