Fertility and Sterility
Volume 94, Issue 4 , Pages 1229-1234 , September 2010

Immunohistochemical detection of aquaporin expression in eutopic and ectopic endometria from women with endometriomas

  • Xiu-Xiu Jiang, M.D.

      Affiliations

    • Department of Gynecology and Obstetrics, Women's Hospital, Zhejiang University Medical College, Zhejiang Province, Hangzhou City, People's Republic of China
    • ,
  • Riu-Jin Wu, Ph.D.

      Affiliations

    • Department of Gynecology and Obstetrics, Women's Hospital, Zhejiang University Medical College, Zhejiang Province, Hangzhou City, People's Republic of China
    • ,
  • Kai-Hong Xu, M.D.

      Affiliations

    • Department of Gynecology and Obstetrics, Women's Hospital, Zhejiang University Medical College, Zhejiang Province, Hangzhou City, People's Republic of China
    • ,
  • Cai-Yun Zhou, B.S.

      Affiliations

    • Department of Pathology, Women's Hospital, Zhejiang University Medical College, Zhejiang Province, Hangzhou City, People's Republic of China
    • ,
  • Xiao-Yan Guo, M.D.

      Affiliations

    • Department of Laboratory, Women's Hospital, Zhejiang University Medical College, Zhejiang Province, Hangzhou City, People's Republic of China
    • ,
  • Ya-Li Sun, M.D.

      Affiliations

    • Department of Laboratory, Women's Hospital, Zhejiang University Medical College, Zhejiang Province, Hangzhou City, People's Republic of China
    • ,
  • Jun Lin, M.D.

      Affiliations

    • Department of Gynecology and Obstetrics, Women's Hospital, Zhejiang University Medical College, Zhejiang Province, Hangzhou City, People's Republic of China
    • Corresponding Author InformationReprint requests: Jun Lin, M.D., Department of Gynecology and Obstetrics, Women's Hospital, Zhejiang University Medical College, 2 Xueshi Road, Zhejiang Province, Hangzhou, Zhejiang, 310006, People's Republic of China (FAX: +086-571-87061878).

Received 29 May 2009 ,Revised 5 August 2009 ,Accepted 20 August 2009.

Reference 

  1. Sampson JA. Peritoneal endometriosis due to the menstrual dissemination of endometrial tissues into the peritoneal cavity. Am J Obstet Gynecol. 1927;14:422–469
  2. Gazvani R, Templeton A. Peritoneal environment, cytokines and angiogenesis in the pathophysiology of endometriosis. Reproduction. 2002;123:217–226
  3. Alessandro R, Kohn EC. Signal transduction targets in invasion. Clin Exp Metastasis. 2002;19:265–273
  4. Friedl P, Wolf K. Tumour-cell invasion and migration: diversity and escape mechanisms. Nat Rev Cancer. 2003;3:362–374
  5. Mareel M, Leroy A. Clinical, cellular, and molecular aspects of cancer invasion. Physiol Rev. 2003;83:337–376
  6. Zhang H, Verkman AS. Evidence against involvement of aquaporin-4 in cell-cell adhesion. J Mol Biol. 2008;382:1136–1143
  7. Papadopoulos MC, Saadoun S, Verkman AS. Aquaporins and cell migration. Pflugers Arch. 2008;465:693–700
  8. Verkman AS. More than just water channels: unexpected cellular roles of aquaporins. J Cell Sci. 2005;118(Pt 15):3225–3232
  9. Pan H, Sun CC, Zhou CY, Huang HF. Expression of aquaporin-1 in normal, hyperplasic and carcinomatous endometria. Int J Gynaecol Obstet. 2008;101:239–244
  10. He RH, Sheng JZ, Luo Q, Jin F, Wang B, Huang HF, et al. Aquaporin-2 expression in human endometrial correlates with serum ovarian steroid hormones. Life Sci. 2006;79:423–429
  11. Yang JH, Shi YF, Cheng Q, Deng L. Expression and localization of aquaporin-5 in the epithelial ovarian tumors. Gynecol Oncol. 2006;100:294–299
  12. Noyes RW, Hertig AT, Rock J. Dating the endometrial biopsy. Am J Obstet Gynecol. 1975;122:262–263
  13. Garfias Y, Navas A, Pérez-Cano HJ, Quevedo J, Villalvazo L, Zenteno JC. Comparative expression analysis of aquaporin-5 (AQP5) in keratoconic and healthy corneas. Mol Vis. 2008;14:756–761
  14. Li X, Yu H, Koide SS. The water channel gene in human uterus. Biochem Mol Biol Int. 1994;32:371–377
  15. Hildenbrand A, Lalitkumar L, Nielsen S, Gemzell-Danielsson K, Stavreus-Evers A. Expression of aquaporin 2 in human endometrial. Fertil Steril. 2006;86:1452–1458
  16. Kobayashi M, Takahashi E, Miyagawa S, Watanabe H, Iguchi T. Chromatin immunoprecipitation-mediated target identification proved aquaporin 5 is regulated directly by estrogen in the uterus. Genes Cells. 2006;11:1133–1143
  17. Domeniconi RF, Orsi AM, Justulin LA. Leme Beu CC, Felisbino SL. Immunolocalization of aquaporins 1, 2 and 7 in rete testis, efferent ducts, epididymis and vas deferens of adult dog. Cell Tissue Res. 2008;332:329–335
  18. Jablonski EM, McConnell NA, Hughes FM, Huet-Hudson YM. Estrogen regulation of aquaporins in the mouse uterus: potential roles in uterine water movement. Biol Reprod. 2003;69:1481–1487
  19. Bulun SE, Lin Z, Imir G, Amin S, Demura M, Martin R, et al. Regulation of aromatase expression in estrogen-responsive breast and uterine disease: from bench to treatment. Pharmacol Rev. 2005;57:359–383
  20. Hudelist G, Czerwenka K, Keckstein J, Haas C, Fink-Retter A, Singer CF, et al. Expression of aromatase and estrogen sulfotransferase in eutopic and ectopic endometrial: evidence for unbalanced estradiol production in endometriosis. Reprod Sci. 2007;14:798–805
  21. Hudelist G, Singer CF, Keckstein J. Matrix metalloproteinases and their role in menstruation and endometriosis. Zentralbl Gynakol. 2005;127:320–324
  22. Klemmt PA, Carver JG, Koninckx P, McVeigh EJ, Mardon HJ. Endometrial cells from women with endometriosis have increased adhesion and proliferative capacity in response to extracellular matrix components: toward a mechanistic model for endometriosis progression. Hum Reprod. 2007;22:3139–3147
  23. Halma J, Hammond MG, Hulka JF, Raj SG, Talbert LM. Retrograde menstruation in healthy women and in patients with endometriosis. Obstet Gynecol. 1984;64:151–154

 X.-X.J. has nothing to disclose. R.-J.W. has nothing to disclose. K.-H.X. has nothing to disclose. C.-Y.Z. has nothing to disclose. X.-Y.G. has nothing to disclose. Y.-L.S. has nothing to disclose. J.L. has nothing to disclose.

PII: S0015-0282(09)03592-4

doi: 10.1016/j.fertnstert.2009.08.053

Fertility and Sterility
Volume 94, Issue 4 , Pages 1229-1234 , September 2010

Article Tools

* Image Usage & Resolution