Fertility and Sterility
Volume 93, Issue 2 , Pages 672-674, 15 January 2010

Comparison of outcomes of conventional intracytoplasmic sperm injection and intracytoplasmic sperm injection using sperm bound to the zona pellucida of immature oocytes

  • Marlene Black, B.Sc.

      Affiliations

    • Reproductive Services and Melbourne IVF, Parkville, Victoria, Australia
    • ,
  • De Yi Liu, Ph.D.

      Affiliations

    • Department of Obstetrics and Gynaecology, University of Melbourne, Royal Women's Hospital, Parkville, Victoria, Australia
    • Corresponding Author InformationReprint requests: De Yi Liu, Ph.D., Department of Obstetrics and Gynaecology, University of Melbourne, Royal Women's Hospital, Parkville, Victoria 3052, Australia (FAX: 61-3-8345 3706).
    • ,
  • Harold Bourne, M.Sc.

      Affiliations

    • Reproductive Services and Melbourne IVF, Parkville, Victoria, Australia
    • ,
  • H.W. Gordon Baker, M.D., Ph.D.

      Affiliations

    • Reproductive Services and Melbourne IVF, Parkville, Victoria, Australia
    • Department of Obstetrics and Gynaecology, University of Melbourne, Royal Women's Hospital, Parkville, Victoria, Australia

Received 28 July 2009; received in revised form 24 August 2009; accepted 25 August 2009. published online 29 October 2009.

This study was to compare the outcomes of conventional (scientist-selected sperm) intracytoplasmic sperm injection (ICSI) and a modified ICSI using zona pellucida (ZP)-bound sperm. Although with 39 couples in each group there was no statistical significance in fertilization, embryo development, implantation, and fetal heart clinical pregnancy rates, the higher implantation and clinical pregnancy rates with ZP-bound sperm encourages further evaluation with larger numbers of subjects using sibling oocytes to determine if the ZP-bound sperm are biologically and functionally superior.

Key Words: Intracytoplasmic sperm injection, zona pellucida-bound sperm, outcomes of ICSI

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 M.B. has nothing to dislcose. D.Y.L. has nothing to disclose. H.B. has nothing to disclose. H.W.G.B. has nothing to disclose.

PII: S0015-0282(09)03617-6

doi:10.1016/j.fertnstert.2009.08.063

Fertility and Sterility
Volume 93, Issue 2 , Pages 672-674, 15 January 2010

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