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The efficacy of multiple-dose methotrexate treatment for unruptured tubal ectopic pregnancy and conversion rate to surgery: a study on 294 cases

Osman Balci, M.D.Corresponding Author Informationemail address, Suna Ozdemir, M.D., Alaa S. Mahmoud, M.D., Ali Acar, M.D., Mehmet C. Colakoglu, M.D.

Received 10 June 2009; received in revised form 11 August 2009; accepted 8 September 2009. published online 04 February 2010.
Corrected Proof

In this prospective study 294 patients diagnosed with ectopic pregnancy (EP) were treated with multiple-dose methotrexate (MTX) to determine the conversion rate to surgery. We concluded that multiple-dose MTX treatment had a low success rate, and the success rate was not related to initial b-hCG value; it was more related to the size of gestational mass before treatment.

Department of Obstetrics and Gynecology, Meram Medicine Faculty, Selcuk University, Konya, Turkey

Corresponding Author InformationReprint requests: Osman Balci, M.D., Department of Obstetrics and Gynecology, Meram Medicine Faculty, Selcuk University, Akyokus, 42080, Konya, Turkey (FAX: 0 90 332 223 6181).

 O.B. has nothing to disclose. S.O. has nothing to disclose. A.S.M. has nothing to disclose. A.A. has nothing to disclose. M.C.C. has nothing to disclose.

PII: S0015-0282(09)03693-0

doi:10.1016/j.fertnstert.2009.09.014