Fertility and Sterility
Volume 93, Issue 7 , Pages 2415-2417, 1 May 2010

The efficacy of multiple-dose methotrexate treatment for unruptured tubal ectopic pregnancy and conversion rate to surgery: a study on 294 cases

Department of Obstetrics and Gynecology, Meram Medicine Faculty, Selcuk University, Konya, Turkey

Received 10 June 2009; received in revised form 11 August 2009; accepted 8 September 2009. published online 04 February 2010.

In this prospective study 294 patients diagnosed with ectopic pregnancy (EP) were treated with multiple-dose methotrexate (MTX) to determine the conversion rate to surgery. We concluded that multiple-dose MTX treatment had a low success rate, and the success rate was not related to initial b-hCG value; it was more related to the size of gestational mass before treatment.

Key Words: Ectopic pregnancy, methotrexate, gestational mass size

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 O.B. has nothing to disclose. S.O. has nothing to disclose. A.S.M. has nothing to disclose. A.A. has nothing to disclose. M.C.C. has nothing to disclose.

PII: S0015-0282(09)03693-0

doi:10.1016/j.fertnstert.2009.09.014

Fertility and Sterility
Volume 93, Issue 7 , Pages 2415-2417, 1 May 2010

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