Fertility and Sterility
Volume 94, Issue 1 , Pages 360-361, June 2010

Peripheral blood CD8+DR+ T-cell count: a potential new immunologic marker of unexplained recurrent abortion

Department of Immunology, Hospital General Universitario Gregorio Marañon, Madrid, Spain

Received 14 July 2009; received in revised form 14 September 2009; accepted 16 September 2009. published online 30 October 2009.

A case–control study was performed to assess whether T-cell activation profile of CD8+ T-cells is associated with unexplained recurrent abortion. Women with abortion had significantly higher percentages (32 ± 11 vs. 24 ± 13%) and absolute numbers (160 ± 78 vs. 114 ± 83 cells/mm3) of CD8+DR+ T-cells than controls.

Key Words: Unexplained recurrent abortion, CD8+DR+, flow cytometry

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 J.C. has nothing to disclose. A.G. has nothing to disclose. N.L. has nothing to disclose. C.C. has nothing to disclose. J.N. has nothing to disclose. E.S. has nothing to disclose.

 Supported by a grant of Foundation Salud 2000, Madrid, Spain, to Javier Carbone.

PII: S0015-0282(09)03713-3

doi:10.1016/j.fertnstert.2009.09.034

Fertility and Sterility
Volume 94, Issue 1 , Pages 360-361, June 2010

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