Fertility and Sterility
Volume 94, Issue 1 , Pages 360-361 , June 2010

Peripheral blood CD8+DR+ T-cell count: a potential new immunologic marker of unexplained recurrent abortion

Received 14 July 2009 ,Revised 14 September 2009 ,Accepted 16 September 2009.

References 

  1. Carbone J, Gallego A, Lanio N, Navarro J, Orera M, Aguaron A, et al. Quantitative abnormalities of peripheral blood distinct T, B, and natural killer cell subsets and clinical findings in obstetric antiphospholipid syndrome. J Rheumatol. 2009;36:1217–1225
  2. Beer AE, Kwak JY, Ruiz JE. Immunophenotypic profiles of peripheral blood lymphocytes in women with recurrent pregnancy losses and in infertile women with multiple failed in vitro fertilization cycles. Am J Reprod Immunol. 1996;35:376–382
  3. Moncharmont P, Bonnard M, Bernaud J, Rigal D, Mellier G, Monier JC. Study of the immune profile of pregnant women. J Gynecol Obstet Biol Reprod (Paris). 1992;21:214–218
  4. Ho HN, Chao KH, Chen CK, Yang YS, Huang SC. Activation status of T and NK cells in the endometrium throughout menstrual cycle and normal and abnormal early pregnancy. Hum Immunol. 1996;49:130–136
  5. Coulam CB, Roussev RG. Increasing circulating T-cell activation markers are linked to subsequent implantation failure after transfer of in vitro fertilized embryos. Am J Reprod Immunol. 2003;50:340–345
  6. Darmochwal-Kolarz D, Saito S, Rolinski J, Tabarkiewicz J, Kolarz B, Leszczynska-Gorzelak B, et al. Activated T lymphocytes in pre-eclampsia. Am J Reprod Immunol. 2007;58:39–45
  7. Viallard JF, Bloch-Michel C, Neau-Cransac M, Taupin JL, Garrigue S, Miossec V, et al. HLA-DR expression on lymphocyte subsets as a marker of disease activity in patients with systemic lupus erythematosus. Clin Exp Immunol. 2001;125:485–491
  8. Couzi L, Merville P, Deminière C, Moreau JF, Combe C, Pellegrin JL, et al. Predominance of CD8+ T lymphocytes among periglomerular infiltrating cells and link to the prognosis of class III and class IV lupus nephritis. Arthritis Rheum. 2007;56:2362–2370
  9. Terashima M, Akita H, Kanazawa K, Shiga N, Matsuda Y, Hirata K, et al. Circulating T-lymphocyte activation in patients with variant angina. Coron Artery Dis. 2002;13:161–168
  10. Carbone J. Immune activation and increased prevalence of thrombosis in HIV infection. J Acquir Immune Defic Syndr. 2007;46:375–376

 J.C. has nothing to disclose. A.G. has nothing to disclose. N.L. has nothing to disclose. C.C. has nothing to disclose. J.N. has nothing to disclose. E.S. has nothing to disclose.

 Supported by a grant of Foundation Salud 2000, Madrid, Spain, to Javier Carbone.

PII: S0015-0282(09)03713-3

doi: 10.1016/j.fertnstert.2009.09.034

Fertility and Sterility
Volume 94, Issue 1 , Pages 360-361 , June 2010

Article Tools