Fertility and Sterility
Volume 94, Issue 2 , Pages 761-763, July 2010

The efficiency of progesterone vaginal gel versus intramuscular progesterone for luteal phase supplementation in gonadotropin-releasing hormone antagonist cycles: a prospective clinical trial

Istanbul Memorial Hospital IVF and Reproductive Genetics Unit, Istanbul, Turkey

Received 16 January 2009; received in revised form 29 September 2009; accepted 3 October 2009. published online 24 November 2009.

We compared the efficiency of progesterone vaginal gel (PVG) with intramuscular progesterone (IMP) supplementation for luteal phase support after in vitro fertilization and embryo transfer in gonadotropin-releasing hormone (GnRH) antagonist cycles. The treatment outcomes were similar for PVG and IMP for luteal support in GnRH-antagonist protocols. With its ease of use, high tolerability by patients, and fewer side effects, PVG can be a successful alternative to IMP.

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 S.K. has nothing to disclose. S.H.K. has nothing to disclose. G.K. has nothing to disclose.

PII: S0015-0282(09)03860-6

doi:10.1016/j.fertnstert.2009.10.004

Fertility and Sterility
Volume 94, Issue 2 , Pages 761-763, July 2010