Growth differentiation factor 9 concentration in the follicular fluid of infertile women with endometriosis

Hendarto, Hendy; Prabowo, Prajitno; Moeloek, Farid Anfasa; Soetjipto, Soetjipto

doi:10.1016/j.fertnstert.2009.10.011

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Volume 94, Issue 2 , Pages 758-760, July 2010

Growth differentiation factor 9 concentration in the follicular fluid of infertile women with endometriosis

Presented at the the World Congress on Endometriosis, Melbourne, Australia, March 11–14, 2008.

Hendy Hendarto, Ph.D.
- Department of Obstetrics and Gynecology, Dr. Soetomo Hospital, Faculty of Medicine, University of Airlangga, Surabaya, Indonesia
- Reprint requests: Hendy Hendarto, Ph.D., Dept. of Obstetrics and Gynecology, Dr. Soetomo Hospital/School of Medicine, University of Airlangga, Surabaya, Indonesia, (FAX: 62 31 5501704).
Prajitno Prabowo, M.D.
- Department of Obstetrics and Gynecology, Dr. Soetomo Hospital, Faculty of Medicine, University of Airlangga, Surabaya, Indonesia
Farid Anfasa Moeloek, Ph.D.
- Department of Obstetrics and Gynecology, Dr. Cipto Mangunkusumo Hospital/Faculty of Medicine, University of Indonesia, Jakarta, Indonesia
Soetjipto Soetjipto, Ph.D.
- Lab of Biochemistry, Faculty of Medicine, University of Airlangga, Surabaya, Indonesia

Received 8 May 2009; received in revised form 2 October 2009; accepted 5 October 2009. published online 19 November 2009.

This study evaluated the level of growth differentiation factor 9 (GDF-9) in the follicular fluid of infertile women with endometriosis. The presence of GDF-9 in follicular fluid of preovulatory follicle was confirmed by Western blotting method in the band of 53 kDa, and GDF-9 concentration in women with severe endometriosis was lower than in those without.