Fertility and Sterility
Volume 94, Issue 2 , Pages 755-757, July 2010

Inherited thrombophilia in infertile women: implication in unexplained infertility

Infertility Center, Section of Gynecology and Obstetrics, Department of Surgery, Tor Vergata University Hospital, Rome, Italy

Received 26 July 2009; received in revised form 4 October 2009; accepted 7 October 2009. published online 24 November 2009.

Many studies evaluating a possible relationship between inherited thrombophilia and the etiology of unexplained infertility have been performed recently. No significant difference in the prevalence of three genetic mutations associated with the increased risk of thrombophilia (Factor V Leiden G1691A, prothrombin G20210A, and methylenetetrahydrofolate reductase [MTHFR] C677 T) was found in 100 infertile women with unexplained infertility when compared with 200 control fertile women without an infertility history.

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 L.C. has nothing to disclose. F.P. has nothing to disclose. L.P. has nothing to disclose. V.Z. has nothing to disclose. E.E. has nothing to disclose.

PII: S0015-0282(09)03874-6

doi:10.1016/j.fertnstert.2009.10.014

Fertility and Sterility
Volume 94, Issue 2 , Pages 755-757, July 2010

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