Fertility and Sterility
Volume 94, Issue 5 , Pages 1627-1631 , October 2010

Cancers, infections, and endocrine diseases in women with endometriosis

  • Julie Anne L. Gemmill, B.A.

      Affiliations

    • Program in Reproductive Endocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland
    • ,
  • Pamela Stratton, M.D.

      Affiliations

    • Program in Reproductive Endocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland
    • ,
  • Sean D. Cleary, Ph.D.

      Affiliations

    • Department of Epidemiology and Biostatistics, School of Public Health and Health Services, George Washington University, Washington, DC
    • ,
  • Mary Lou Ballweg, B.A.

      Affiliations

    • Endometriosis Association International Headquarters, Milwaukee, Wisconsin
    • ,
  • Ninet Sinaii, Ph.D.

      Affiliations

    • Program in Reproductive Endocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland
    • Biostatistics and Clinical Epidemiology Service, Clinical Center, National Institutes of Health, Bethesda, Maryland
    • Corresponding Author InformationReprint requests: Ninet Sinaii, Ph.D., Biostatistics and Clinical Epidemiology Service, National Institutes of Health Clinical Center, 10 Center Drive, Building 10, Room 2N-228, Bethesda, Maryland 20891-1871 (FAX: 301-496-0457).

Received 14 April 2009 ,Revised 14 July 2009 ,Accepted 29 July 2009.

References 

  1. Sinaii N, Cleary SD, Ballweg ML, Nieman LK, Stratton P. High rates of autoimmune and endocrine disorders, fibromyalgia, chronic fatigue syndrome and atopic diseases among women with endometriosis: a survey analysis. Hum Reprod. 2002;17:2715–2724
  2. Giudice LC, Kao LC. Endometriosis. Lancet. 2004;364:1789–1799
  3. Bulun SE. Endometriosis. N Engl J Med. 2009;360:268–279
  4. Brinton LA, Gridley G, Persson I, Baron J, Bergqvist A. Cancer risk after a hospital discharge diagnosis of endometriosis. Am J Obstet Gynecol. 1997;176:572–579
  5. Melin A, Sparen P, Persson I, Bergqvist A. Endometriosis and the risk of cancer with special emphasis on ovarian cancer. Hum Reprod. 2006;21:1237–1242
  6. Modugno F, Ness RB, Allen GO, Schildkraut JM, Davis FG, Goodman MT. Oral contraceptive use, reproductive history, and risk of epithelial ovarian cancer in women with and without endometriosis. Am J Obstet Gynecol. 2004;191:733–740
  7. Brinton LA, Lamb EJ, Moghissi KS, Scoccia B, Althuis MD, Mabie JE, et al. Ovarian cancer risk associated with varying causes of infertility. Fertil Steril. 2004;82:405–414
  8. Riman T, Nilsson S, Persson IR. Review of epidemiological evidence for reproductive and hormonal factors in relation to the risk of epithelial ovarian malignancies. Acta Obstet Gynecol Scand. 2004;83:783–795
  9. Bruner-Tran KL, Yeaman GR, Crispens MA, Igarashi TM, Osteen KG. Dioxin may promote inflammation-related development of endometriosis. Fertil Steril. 2008;89:1287–1298
  10. Melin A, Sparen P, Bergqvist A. The risk of cancer and the role of parity among women with endometriosis. Hum Reprod. 2007;22:3021–3026
  11. Kvaskoff M, Mesrine S, Fournier A, Boutron-Ruault MC, Clavel-Chapelon F. Personal history of endometriosis and risk of cutaneous melanoma in a large prospective cohort of French women. Arch Intern Med. 2007;167:2061–2065
  12. Brinton LA, Westhoff CL, Scoccia B, Lamb EJ, Althuis MD, Mabie JE, et al. Causes of infertility as predictors of subsequent cancer risk. Epidemiology. 2005;16:500–507
  13. Weiss HA, Brinton LA, Potischman NA, Brogan D, Coates RJ, Gammon MD, et al. Breast cancer risk in young women and history of selected medical conditions. Int J Epidemiol. 1999;28:816–823
  14. Moseson M, Koenig KL, Shore RE, Pasternack BS. The influence of medical conditions associated with hormones on the risk of breast cancer. Int J Epidemiol. 1993;22:1000–1009
  15. Steed H, Chapman W, Laframboise S. Endometriosis-associated ovarian cancer: a clinicopathologic review. J Obstet Gynaecol Can. 2004;26:709–715
  16. Borgfeldt C, Andolf E. Cancer risk after hospital discharge diagnosis of benign ovarian cysts and endometriosis. Acta Obstet Gynecol Scand. 2004;83:395–400
  17. Obata K, Morland SJ, Watson RH, Hitchcock A, Chenevix-Trench G, Thomas EJ, et al. Frequent PTEN/MMAC mutations in endometrioid but not serous or mucinous epithelial ovarian tumors. Cancer Res. 1998;58:2095–2097
  18. Baxter SW, Thomas EJ, Campbell IG. GSTM1 null polymorphism and susceptibility to endometriosis and ovarian cancer. Carcinogenesis. 2001;22:63–65
  19. Baranova H, Bothorishvilli R, Canis M, Albuisson E, Perriot S, Glowaczower E, et al. Glutathione S-transferase M1 gene polymorphism and susceptibility to endometriosis in a French population. Mol Hum Reprod. 1997;3:775–780
  20. Martini M, Ciccarone M, Garganese G, Maggiore C, Evangelista A, Rahimi S, et al. Possible involvement of hMLH1, p16(INK4a) and PTEN in the malignant transformation of endometriosis. Int J Cancer. 2002;102:398–406
  21. Berchuck A, Schildkraut JM, Wenham RM, Calingaert B, Ali S, Henriott A, et al. Progesterone receptor promoter +331A polymorphism is associated with a reduced risk of endometrioid and clear cell ovarian cancers. Cancer Epidemiol Biomarkers Prev. 2004;13:2141–2147
  22. Cottreau CM, Ness RB, Modugno F, Allen GO, Goodman MT. Endometriosis and its treatment with danazol or lupron in relation to ovarian cancer. Clin Cancer Res. 2003;9:5142–5144
  23. Sinaii N, Cleary SD, Younes N, Ballweg ML, Stratton P. Treatment utilization for endometriosis symptoms: a cross-sectional survey study of lifetime experience. Fertil Steril. 2007;87:1277–1286
  24. Hornstein MD, Thomas PP, Sober AJ, Wyshak G, Albright NL, Frisch RE. Association between endometriosis, dysplastic naevi and history of melanoma in women of reproductive age. Hum Reprod. 1997;12:143–145
  25. Surveillance, Epidemiology, and End Results (SEER). http://seer.cancer.gov. Accessed on January 9, 2006.
  26. USDHHS Vital and Health Statistics: current estimates from the National Health Interview Survey, 1996.
  27. Geiger AM, Foxman B, Gillespie BW. The epidemiology of vulvovaginal candidiasis among university students. Am J Pub Health. 1995;85:1146–1148
  28. First Consult. http://www.firstconsult.com/home/framework/fs_main.htm. Accessed on June 9, 2008.
  29. Mononucleosis and Epstein-Barr Virus Infection. http://www.emedicine.com/PED/topic705.htm. Accessed on March 12, 2009.
  30. Addison's Disease. http://www.emedicine.com/derm/topic761.htm#section∼introduction. Accessed on March 12, 2009.
  31. Levy D, Savage D. Prevalence and clinical features of mitral valve prolapse. Am Heart J. 1987;113:1281–1290

 J.A.L.G. has nothing to disclose. P.S. has nothing to disclose. S.D.C. has nothing to disclose. M.L.B. has nothing to disclose. N.S. has nothing to disclose.

 The 1998 Endometriosis Association Survey was supported by an unrestricted educational grant from Zeneca Pharmaceuticals. The research for this study was supported by the Intramural Program of the Eunice Kennedy Shriver National Institute of Child Health and Human Development and the Clinical Center, National Institute of Health, Bethesda, Maryland, and the Endometriosis Association, International Headquarters, Milwaukee, Wisconsin.

PII: S0015-0282(09)03880-1

doi: 10.1016/j.fertnstert.2009.07.1698

Fertility and Sterility
Volume 94, Issue 5 , Pages 1627-1631 , October 2010

Article Tools