Fertility and Sterility
Volume 93, Issue 8 , Pages 2734-2737 , 15 May 2010

Early demonstration of postoperative adhesions in a rodent model

  • Frank D. Yelian, M.D., Ph.D.
    • ,
  • Valerie I. Shavell, M.D.
    • ,
  • Michael P. Diamond, M.D.

      Affiliations

    • Corresponding Author InformationReprint requests: Michael P. Diamond, M.D., Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Wayne State University School of Medicine, 3800 Woodward Avenue, Suite 320-D, Detroit, MI 48201 (TEL: 313-993-4523; FAX: 313-993-4534).

Received 12 November 2009 ,Revised 13 January 2010 ,Accepted 20 January 2010.

References 

  1. Liakakos T, Thomakos N, Fine PM, Dervenis C, Young RL. Peritoneal adhesions: etiology, pathophysiology, and clinical significance. Recent advances in prevention and management. Dig Surg. 2001;18:260–273
  2. La Morte AI, Diamond MP. Adhesion formation after laparoscopy. Prog Clin Biol Res. 1993;381:51–58
  3. Shafer M, Krahenbuhl L, Buchler MW. Comparison of adhesion formation in open and laparoscopic surgery. Dig Surg. 1998;15:148–152
  4. Gonzales-Quintero VH, Cruz-Pachano FE. Preventing adhesions in obstetric and gynecologic surgical procedures. Rev Obstet Gynecol. 2009;2:38–45
  5. Awonuga AO, Saed GH, Diamond MP. Laparoscopy in gynecologic surgery: adhesion development, prevention, and use of adjunctive therapies. Clin Obstet Gynecol. 2009;52:412–422
  6. Practice Committee of the American Society for Reproductive Medicine, Society of Reproductive Surgeons. Pathogenesis, consequences, and control of peritoneal adhesions in gynecologic surgery. Fertil Steril. 2007;88:21–26
  7. Imudia AN, Kumar S, Saed GM, Diamond MP. Pathogenesis of intra-abdominal and pelvic adhesion development. Semin Reprod Med. 2008;26:289–297
  8. Diamond MP, Daniell JF, Feste J, Surrey MW, McLaughlin DS, Friedman S, et al. Adhesion reformation and de novo adhesion formation after reproductive pelvic surgery. Fertil Steril. 1987;47:864–866
  9. Freeman ML, Saed GM, Elhammady EF, Diamond MP. Expression of transforming growth factor beta isoform mRNA in injured peritoneum that healed with adhesions and without adhesions and in uninjured peritoneum. Fertil Steril. 2003;80:708–713
  10. Burns JW, Skinner K, Colt MJ, Burgess L, Rose R, Diamond MP. A hyaluronate based gel for the prevention of postsurgical adhesions: evaluation in two animal species. Fertil Steril. 1996;66:814–821
  11. Zamir G, Bloom AI, Reissman P. Prevention of intestinal adhesions after laparotomy in a rat model—a randomized prospective study. Res Exp Med (Berl). 1998;197:349–353
  12. Lucas PA, Warejcka DJ, Zhang LM, Newman WH, Young HE. Effect of rat mesenchymal stem cells on development of abdominal adhesions after surgery. J Surg Res. 1996;62:229–232
  13. Dargenio R, Cimino C, Ragusa G, Garcea N, Stella C. Pharmacological prevention of postoperative adhesions experimentally induced in the rat. Acta Eur Fertil. 1986;17:267–272
  14. Aksakal O, Yilmaz B, Gungor T, Sirvan L, Sut N, Inan I, et al. A randomised controlled trial on melatonin and rosiglitazone for prevention of adhesion formation in a rat uterine horn model. Arch Gynecol Obstet. 2009;[Epub ahead of print]
  15. Boland JM, Weigel RJ. Formation and prevention of postoperative abdominal adhesions. J Surg Res. 2004;132:3–12
  16. Chammas R, Veiga SS, Travassos LR, Brentani RR. Functionally distinct roles for glycosylation of α and β integrin chains in cell-matrix interactions. Proc Natl Acad Sci U S A. 1993;90:1795–1799
  17. Brakebusch C, Fassler R. β1 integrin function in vivo: adhesion, migration and more. Cancer Metastasis Rev. 2005;24:403–411
  18. Harris ES, Morgan RF, Rodeheaver GT. Analysis of the kinetics of peritoneal adhesion formation in the rat and evaluation of potential antiadhesive agents. Surgery. 1995;117:663–669

 F.D.Y. has nothing to disclose. V.I.S. has nothing to disclose. M.P.D. has performed contract research for Neurocrine, Boehringer Ingelheim, Busante, Ethicon, and Wyeth; been a consultant for Genzyme, Omrix, Neomend, ARC, Baxter and Serono; and member of the board of directors for ARC.

PII: S0015-0282(10)00129-9

doi: 10.1016/j.fertnstert.2010.01.054

Fertility and Sterility
Volume 93, Issue 8 , Pages 2734-2737 , 15 May 2010

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