Fertility and Sterility
Volume 94, Issue 6 , Pages 2161-2166 , November 2010

Effects of metformin and leuprolide acetate on insulin resistance and testosterone levels in nondiabetic postmenopausal women: a randomized, placebo-controlled trial

  • Shrita M. Patel, M.D., M.S.C.E.

      Affiliations

    • Division of Endocrinology, Diabetes, and Metabolism, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
    • Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
    • ,
  • Nayyar Iqbal, M.D., M.S.C.E.

      Affiliations

    • Section of Endocrinology, Diabetes, and Metabolism, Philadelphia VA Medical Center, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
    • ,
  • Shailja Kaul, M.B.B.S.

      Affiliations

    • Division of Endocrinology, Diabetes, and Metabolism, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
    • ,
  • Sarah J. Ratcliffe, Ph.D.

      Affiliations

    • Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
    • ,
  • Michael R. Rickels, M.D., M.S.

      Affiliations

    • Division of Endocrinology, Diabetes, and Metabolism, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
    • ,
  • Muredach P. Reilly, M.B., M.S.C.E.

      Affiliations

    • Cardiovascular Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
    • ,
  • Theresa Scattergood, R.N., M.S.N.

      Affiliations

    • Division of Endocrinology, Diabetes, and Metabolism, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
    • ,
  • Arpita Basu, M.B.B.S.

      Affiliations

    • Division of Endocrinology, Diabetes, and Metabolism, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
    • ,
  • Carissa Fuller, C.R.N.P.

      Affiliations

    • Division of Endocrinology, Diabetes, and Metabolism, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
    • ,
  • Anne R. Cappola, M.D., Sc.M.

      Affiliations

    • Division of Endocrinology, Diabetes, and Metabolism, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
    • Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
    • Corresponding Author InformationReprint requests: Anne R. Cappola, M.D., Sc.M., University of Pennsylvania School of Medicine, 764 CRB, 415 Curie Blvd., Philadelphia, PA 19104 (FAX: (215) 898-5408).

Received 11 November 2009 ,Revised 20 January 2010 ,Accepted 25 January 2010.

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 S.M.P. has nothing to disclose. N.I. has nothing to disclose. S.K. has nothing to disclose. S.J.R. has nothing to disclose. M.R.R. has nothing to disclose. M.P.R. has nothing to disclose. T.S. has nothing to disclose. A.B. has nothing to disclose. C.F. has nothing to disclose. A.R.C. has nothing to disclose.

 Supported by K23 AG19161 from the National Institute on Aging, UL1RR024134 from the National Center for Research Resources, P30 DK19525 from the National Institute of Diabetes and Digestive and Kidney Diseases, the John A. Hartford Foundation, and the University of Pennsylvania Institute for Diabetes, Obesity, and Metabolism. The views expressed are those of the authors and do not necessarily represent the official views of the National Institutes of Health.

PII: S0015-0282(10)00139-1

doi: 10.1016/j.fertnstert.2010.01.064

Fertility and Sterility
Volume 94, Issue 6 , Pages 2161-2166 , November 2010

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