Fertility and Sterility
Volume 94, Issue 3 , Pages 1097.e13-1097.e15 , August 2010

Prolactinoma induced by estrogen and cyproterone acetate in a male-to-female transsexual

Received 15 December 2009 ,Accepted 27 January 2010.

References 

  1. Gooren LJ, Giltay EJ, Bunck MC. Long-term treatment of transsexuals with cross-sex hormones: extensive personal experience. J Clin Endocrinol Metab. 2008;93:19–25
  2. Gooren LJ, Assies J, Asscheman H, de Slegte R, van Kessel H. Estrogen-induced prolactinoma in a man. J Clin Endocrinol Metab. 1988;66:444–446
  3. Kovacs K, Stefaneanu L, Ezzat S, Smyth HS. Prolactin-producing pituitary adenoma in a male-to-female transsexual patient with protracted estrogen administration: a morphologic study. Arch Pathol Lab Med. 1994;118:562–565
  4. Serri O, Noiseux D, Robert F, Hardy J. Lactotroph hyperplasia in an estrogen treated male-to-female transsexual patient. J Clin Endocrinol Metab. 1996;81:3177–3179
  5. Asscheman H, Gooren LJ, Assies J, Smits JP, de Slegte R. Prolactin levels and pituitary enlargement in hormone-treated male-to-female transsexuals. Clin Endocrinol (Oxf). 1988;28:583–588
  6. Bunck MC, Debono M, Giltay EJ, Verheijen AT, Diamant M, Gooren LJ. Autonomous prolactin secretion in two male-to-female transgender patients using conventional oestrogen dosages. BMJ Case Reports. Published online August 10, 2009.
  7. Willemse PH, Dikkeschei LD, Mulder NH, van der Ploeg E, Sleijfer DT, de Vries EG. Clinical and endocrine effects of cyproterone acetate in postmenopausal patients with advanced breast cancer. Eur J Cancer Clin Oncol. 1998;24:417–421
  8. Heaney AP, Fernando M, Melmed S. Functional role of estrogen in pituitary tumour pathogenesis. J Clin Invest. 2002;109:277–283
  9. Piroli G, Lima AE, Díaz-Torga G, De Nicola AF. Biochemical parameters in the anterior pituitary during the course of tumorigenesis induced by diethylstilbestrol treatment. J Steroid Biochem Mol Biol. 1994;51:183–189
  10. Xu RK, Wu XM, Di AK, Xu JN, Pang CS, Pang SF. Pituitary prolactin-secreting tumor formation: recent developments. Biol Signals Recept. 2000;9:1–20

 K.G-M. has nothing to disclose. A.M-G. has nothing to disclose. M.R. has nothing to disclose. M.G-B. has nothing to disclose. A.H-M. has nothing to disclose.

PII: S0015-0282(10)00151-2

doi: 10.1016/j.fertnstert.2010.01.076

Fertility and Sterility
Volume 94, Issue 3 , Pages 1097.e13-1097.e15 , August 2010

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