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Fertility and Sterility
Volume 95, Issue 1
, Pages 152-157
, January 2011
A randomized trial of the effect of testosterone and estrogen on verbal fluency, verbal memory, and spatial ability in healthy postmenopausal women
References
- . Hormonal influence on the central nervous system. Maturitas. 2002;43:11–17
- . Estrogen actions throughout the brain. Recent Prog Hormone Res. 2002;57:357–384
- . Non-genomic actions of sex steroid hormones. Eur J Endocrinol. 2003;148:281–292
- . Sex and cognition. Cambridge, MA: MIT Press; 1999;
- . Sex differences in cognitive abilities. 3rd ed.. Mahwah, NJ: Erlbaum; 2000;
- . Sex hormones influence human cognitive pattern. Neuro Endocrinol Lett. 2002;23:67–77
- . Reciprocal effects of hormonal fluctuations on human motor and perceptual-spatial skills. Behav Neurosci. 1988;102:456–459
- . Variations in sex related cognitive abilities across the menstrual cycle. Brain Cogn. 1990;14:26–43
- . Differences in the relationship of menstrual cycle phase to spatial performance on two- and three-dimensional tasks. Horm Behav. 1997;32:167–175
- Associations between circulation sex steroid hormones and cognition in normal elderly women. Neurology. 2000;54:599–603
- . Implicit memory varies across the menstrual cycle: estrogen effects in young women. Neuropsychologia. 2002;40:518–529
- . No difference in cognitive performance between phases of the menstrual cycle. Psychoneuroendocrinol. 1993;18:521–531
- . Verbal and spatial functions across the menstrual cycle in healthy young women. Psychoneuroendocrinology. 2002;27:835–841
- . Endogenous estrogen is not associated with cognitive performance before, during, or after menopause. Menopause. 2007;14:425–431
- Effects of the menopause transition and hormone use on cognitive performance in midlife women. Neurology. 2009;72:1850–1857
- . The nature of the effect of female gonadal hormone replacement therapy on cognitive function in post-menopausal women: a meta-analysis. Neuroscience. 2000;101:485–512
- . Enhanced verbal memory in nondemented elderly women receiving hormone-replacement therapy. Am J Psychatry. 2001;158:227–233
- . Verified HT improves episodic memory performance in healthy postmenopausal women. Aging Neuropsychol Cogn. 2006;13:291–307
- Effect of estrogen plus progestin on global cognitive function in postmenopausal women: the women's health initiative memory study: a randomized controlled trial. JAMA. 2003;289:2663–2672
- Conjugated equine estrogens and global cognitive function in postmenopausal women: women's health initiative memory study. JAMA. 2004;291:2959–2968
- Effects of combination estrogen plus progestin hormone treatment on cognition and affect. J Clin Endocrinol Metab. 2006;91:1802–1810
- Effects of conjugated equine estrogens on cognition and affect in postmenopausal women with prior hysterectomy. J Clin Endocrinol Metab. 2009;94:4152–4161
- . Estrogen and/or androgen replacement therapy and cognitive functioning in surgically menopausal women. Psychoneuroendocrinology. 1988;13:345–357
- Better oral reading and short-term memory in midlife, postmenopausal women taking estrogen. Menopause. 2003;10:420–426
- Estrogen therapy selectively enhances prefrontal cognitive processes: a randomized, double-blind, placebo-controlled study with functional magnetic resonance imaging in perimenopausal and recently postmenopausal women. Menopause. 2006;13:411–422
- . Brain aging modulates the neuroprotective effects of estrogen on selective aspects of cognition in women: a critical review. Front Neuroendocrinol. 2008;29:88–113
- . HT and cognitive function. Hum Reprod Update. 2009;15:667–681
- . Testosterone and cognitive function: current clinical evidence of a relationship. Eur J Endocrinol. 2006;155:773–781
- . Thinking with your gonads: testosterone and cognition. Trend Cogn Sci. 2006;10:77–82
- . The association between endogenous free testosterone and cognitive performance: a population-based study in 35 to 90 year-old men and women. Psychoneuroendocrinology. 2006;31:565–576
- . Sex hormones affect spatial abilities during the menstrual cycle. Behav Neurosci. 2000;114:1245–1250
- . A single administration of testosterone improves visuospatial ability in young women. Psychoneuroendocrinology. 2004;29:612–617
- . Effects of testosterone administration on selective aspects of object-location memory in healthy young women. Psychoneuroendocrinology. 2000;25:563–575
- Effects of testosterone replacement in androgen-deficient women with hypopituitarism: a randomized, double-blind, placebo-controlled study. J Clin Endocrinol Metab. 2006;91:1683–1690
- . A randomized trial of the effect of estrogen and testosterone on economic behavior. Proc Natl Acad Sci U S A. 2009;106:6535–6538
- . Hormone replacement therapy: the benefits in tailoring the regimen and dose. Maturitas. 2001;40:195–201
- . Addition of testosterone to estrogen replacement therapy in oophorectomized women: effects on sexuality and well-being. Climacteric. 2002;5:357–365
- . Calculation of free and bound fractions of testosterone and estradiol-17β to human plasma proteins at body temperature. J Steroid Biochem. 1982;16:801–810
- . Sex differences favouring women in verbal but not in visuospatial episodic memory. Neuropsychologia. 2001;15:165–173
- . Gender differences in episodic memory. Mem Cognit. 1997;25:801–811
- . Mental rotations: a group test of three-dimensional spatial visualisation. Percept Mot Skills. 1978;47:599–604
- . Mental rotation of three-dimensional objects. Science. 1971;171:701–703
- . Estrogen and progestogen use in postmenopausal women: 2010 position statement of the North American Menopause Society. Menopause. 2010;17:242–255
- Transdermal testosterone treatment in women with impaired sexual function after oophorectomy. New Engl J Med. 2000;343:682–688
- Testosterone for low libido in menopausal women not taking estrogen therapy. N Engl J Med. 2008;359:2005–2017
- Effects of ultra-low-dose transdermal estradiol on cognition and health-related quality of life. Arch Neurol. 2006;63:945–950
- . Testosterone administration in women with anorexia nervosa. J Clin Endocrinol Metab. 2005;90:1428–1433
- . Androgen replacement therapy in Turner syndrome: a pilot study. J Clin Endocrinol Metab. 2009;94:4820–4827
- . Update on research and treatment of premenstrual dysphoric disorder. Harv Rev Psychiatry. 2009;17:120–137
- . Role of testosterone in the treatment of hypoactive sexual desire disorder. Maturitas. 2009;63:152–159
Supported by the Swedish Research Council (No. 20324), Karolinska Institutet, Jan Wallander and Tom Hedelius Foundation, and the Swedish Council for Working Life and Social Research.
L. K-M. has nothing to disclose. N.Z. has nothing to disclose. A.F.R. has nothing to disclose. T.E. has nothing to disclose. B.v.S. has nothing to disclose. M.J. has nothing to disclose. A.L.H. has nothing to disclose.
PII: S0015-0282(10)00943-X
doi: 10.1016/j.fertnstert.2010.05.062
© 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
« Previous
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Fertility and Sterility
Volume 95, Issue 1
, Pages 152-157
, January 2011

