Fertility and Sterility
Volume 95, Issue 3 , Pages 959-963 , 1 March 2011

Perinatal outcome of singleton siblings born after assisted reproductive technology and spontaneous conception: Danish national sibling-cohort study

  • Anna-Karina Aaris Henningsen, M.D.

      Affiliations

    • Fertility Clinic, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
    • Corresponding Author InformationReprint requests: Anna-Karina Aaris Henningsen, M.D., Fertility Clinic, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen, Denmark.
    • ,
  • Anja Pinborg, M.D.Sc.

      Affiliations

    • Fertility Clinic, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
    • ,
  • Øjvind Lidegaard, M.D.Sc.

      Affiliations

    • Department of Gynecology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
    • ,
  • Christina Vestergaard, M.P.H.

      Affiliations

    • Department of Gynecology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
    • ,
  • Julie Lyng Forman, M.Sc., Ph.D.

      Affiliations

    • Department of Biostatistics, University of Copenhagen, Copenhagen, Denmark
    • ,
  • Anders Nyboe Andersen, M.D.Sc.

      Affiliations

    • Fertility Clinic, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

Received 7 April 2010 ,Revised 6 July 2010 ,Accepted 22 July 2010.

References 

  1. Nyboe Andersen A, Goossens V, Bhattacharya S, Ferraretti AP, Kupka MS, de Mouzon J, et al. Assisted reproductive technology and intrauterine inseminations in Europe, 2005: results generated from European registers by ESHRE: ESHRE. The European IVF Monitoring Programme (EIM), for the European Society of Human Reproduction and Embryology (ESHRE). Hum Reprod. 2009;24:1267–1287
  2. Kallen B, Finnstrom O, Nygren KG, Olausson PO. In vitro fertilization in Sweden: child morbidity including cancer risk. Fertil Steril. 2005;84:605–610
  3. Thurin A, Hausken J, Hillensjo T, Jablonowska B, Pinborg A, Strandell A, et al. Elective single-embryo transfer versus double-embryo transfer in in vitro fertilization. N Engl J Med. 2004;351:2392–2402
  4. Helmerhorst FM, Perquin DA, Donker D, Keirse MJ. Perinatal outcome of singletons and twins after assisted conception: a systematic review of controlled studies. BMJ. 2004;328:261
  5. Basso O, Baird DD. Infertility and preterm delivery, birthweight, and Caesarean section: a study within the Danish National Birth Cohort. Hum Reprod. 2003;18:2478–2484
  6. Draper ES, Kurinczuk JJ, Abrams KR, Clarke M. Assessment of separate contributions to perinatal mortality of infertility history and treatment: a case-control analysis. Lancet. 1999;353:1746–1749
  7. Romundstad LB, Romundstad PR, Sunde A, von Düring V, Skjaerven R, Gunnell D, et al. Effects of technology or maternal factors on perinatal outcome after assisted fertilisation: a population-based cohort study. Lancet. 2008;372:737–743
  8. Kallen B, Finnstrom O, Nygren KG, Olausson PO. In vitro fertilization (IVF) in Sweden: infant outcome after different IVF fertilization methods. Fertil Steril. 2005;84:611–617
  9. Shih W, Rushford DD, Bourne H, Garrett C, McBain JC, Healy DL, et al. Factors affecting low birthweight after assisted reproduction technology: difference between transfer of fresh and cryopreserved embryos suggests an adverse effect of oocyte collection. Hum Reprod. 2008;23:1644–1653
  10. Pinborg A, Loft A, Aaris Henningsen AK, Rasmussen S, Nyboe AA. Infant outcome of 957 singletons born after frozen embryo replacement: The Danish National Cohort Study 1995-2006. Fertil Steril. 2009;[Epub ahead of print]
  11. Wang YA, Sullivan EA, Black D, Dean J, Bryant J, Chapman M. Preterm birth and low birth weight after assisted reproductive technology-related pregnancy in Australia between 1996 and 2000. Fertil Steril. 2005;83:1650–1658
  12. Wennerholm UB, Soderstrom-Anttila V, Bergh C, Aittomaki K, Hazekamp J, Nygren KG, et al. Children born after cryopreservation of embryos or oocytes: a systematic review of outcome data. Hum Reprod. 2009;24:2158–2172
  13. Belva F, Henriet S, Van den Abbeel E, Camus M, Devroey P, Van der Elst J, et al. Neonatal outcome of 937 children born after transfer of cryopreserved embryos obtained by ICSI and IVF and comparison with outcome data of fresh ICSI and IVF cycles. Hum Reprod. 2008;23:2227–2238
  14. The Danish Fertility Society: A summary of intrauterine insemination (IUI) treatments performed in Denmark year 2009. Available at: http://www.fertilitetsselskab.dk/årsrapporter/2009/IUI. Accessed April 20, 2010.
  15. Nygren KG, Finnstrom O, Kallen B, Olausson PO. Population-based Swedish studies of outcomes after in vitro fertilisation. Acta Obstet Gynecol Scand. 2007;86:774–782
  16. Stephansson O, Kieler H, Granath F, Falconer H. Endometriosis, assisted reproduction technology, and risk of adverse pregnancy outcome. Hum Reprod. 2009;24:2341–2347
  17. Griesinger G, Kolibianakis EM, Diedrich K, Ludwig M. Ovarian stimulation for IVF has no quantitative association with birthweight: a registry study. Hum Reprod. 2008;23:2549–2554

 A-K.A.H. has nothing to disclose. A.P. has nothing to disclose. Ø.L. has nothing to disclose. C.V. has nothing to disclose. J.L.F. has nothing to disclose. A.N.A. has nothing to disclose.

PII: S0015-0282(10)02201-6

doi: 10.1016/j.fertnstert.2010.07.1075

Fertility and Sterility
Volume 95, Issue 3 , Pages 959-963 , 1 March 2011

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