Fertility and Sterility
Volume 95, Issue 1 , Pages 327-329, January 2011

Hemorheologic profile in healthy women undergoing controlled ovarian stimulation

  • Cinzia Fatini, M.D, Ph.D.

      Affiliations

    • Department of Medical and Surgical Critical Care, Thrombosis Center, University of Florence, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy
    • Corresponding Author InformationReprint requests: Cinzia Fatini, M.D., Ph.D., Department of Medical and Surgical Critical Care, University of Florence, Viale Morgagni 85, 50134 Florence, Italy (FAX: 39-0557949929).
    • ,
  • Lucia Mannini, M.D.

      Affiliations

    • Department of Medical and Surgical Critical Care, Thrombosis Center, University of Florence, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy
    • ,
  • Elena Sticchi, B.S.

      Affiliations

    • Department of Medical and Surgical Critical Care, Thrombosis Center, University of Florence, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy
    • ,
  • Maria Novella Milanini, M.D.

      Affiliations

    • Department of Gynecology, Perinatology and Reproductive Medicine, University of Florence, Florence, Italy
    • ,
  • Gabriele Cioni, M.D.

      Affiliations

    • Department of Medical and Surgical Critical Care, Thrombosis Center, University of Florence, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy
    • ,
  • Agatina Alessandrello Liotta, B.S.

      Affiliations

    • Department of Medical and Surgical Critical Care, Thrombosis Center, University of Florence, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy
    • ,
  • Rosanna Abbate, M.D.

      Affiliations

    • Department of Medical and Surgical Critical Care, Thrombosis Center, University of Florence, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy
    • ,
  • Ivo Noci, M.D.

      Affiliations

    • Department of Gynecology, Perinatology and Reproductive Medicine, University of Florence, Florence, Italy

Received 4 February 2010; received in revised form 15 June 2010; accepted 23 July 2010. published online 02 September 2010.

We investigated the hemorheologic profile in 110 women undergoing controlled ovarian stimulation and provide evidence that smokers and women with body mass index >25 kg/m2 exhibit alterations of rheologic profile. A progressive increase of whole-blood viscosity throughout the ovarian stimulation cycle was observed; deformability and aggregation of erythrocytes decreased from baseline to the beginning of recombinant FSH administration, then remained unchanged throughout the next days; hematocrit mildly decreased during the last days of recombinant FSH administration; and fibrinogen and cholesterol levels decreased and increased, respectively, throughout the stimulation cycle.

Key Words: Infertility, controlled ovarian stimulation, rheological parameters, blood viscosity

 

 F.C. has nothing to disclose. L.M. has nothing to disclose. E.S. has nothing to disclose. M.N.M. has nothing to disclose. G.C. has nothing to disclose. A.A.L. has nothing to disclose. R.A. has nothing to disclose. I.N. has nothing to disclose.

PII: S0015-0282(10)02204-1

doi:10.1016/j.fertnstert.2010.07.1078

Fertility and Sterility
Volume 95, Issue 1 , Pages 327-329, January 2011

Article Tools