Fertility and Sterility
Volume 71, Issue 4 , Pages 671-674 , April 1999

Adrenal androgen excess in hyperandrogenism: relation to age and body mass

Presented at the 80th Annual Meeting of The Endocrine Society, New Orleans, Louisiana, June 24–27, 1998.

  • Carlos Morán, M.D. (M.Sc.)

      Affiliations

    • Research Unit of Reproductive Medicine, Instituto Mexicano del Seguro Social.
    • Department of Obstetrics and Gynecology, The University of Alabama at Birmingham.
    • Instituto Mexicano del Seguro Social, Mexico City, Mexico
    • The University of Alabama at Birmingham, Birmingham, Alabama, USA
    • ,
  • Eric Knochenhauer, M.D.

      Affiliations

    • Department of Obstetrics and Gynecology, The University of Alabama at Birmingham.
    • The University of Alabama at Birmingham, Birmingham, Alabama, USA
    • ,
  • Larry R Boots, Ph.D.

      Affiliations

    • Department of Obstetrics and Gynecology, The University of Alabama at Birmingham.
    • The University of Alabama at Birmingham, Birmingham, Alabama, USA
    • ,
  • Ricardo Azziz, M.D. (M.P.H.)

      Affiliations

    • Department of Medicine, The University of Alabama at Birmingham.
    • The University of Alabama at Birmingham, Birmingham, Alabama, USA

Received 29 July 1998 ,Revised 30 November 1998 ,Accepted 30 November 1998.

References 

  1. Knochenhauer ES, Key TJ, Kahsar-Miller M, Waggoner W, Boots LR, Azziz R. Prevalence of the polycystic ovarian syndrome in unselected black and white women of the southeastern United States (a prospective study). J Clin Endocrinol Metab. 1998;83:3078–3082
  2. Wild RA, Umstot ES, Andersen RN, Ranney GB, Givens JR. Androgen parameters and their correlation with body weight in one hundred thirty-eight women thought to have hyperandrogenism. Am J Obstet Gynecol. 1983;146:602–606
  3. Carmina E, Koyama T, Chang L, Stanczyk FZ, Lobo RA. Does ethnicity influence the prevalence of adrenal hyperandrogenism and insulin resistance in polycystic ovary syndrome?. Am J Obstet Gynecol. 1992;167:1807–1812
  4. Orentreich N, Brind JL, Rizer RL, Vogelman JH. Age changes and sex differences in serum dehydroepiandrosterone sulfate concentrations throughout adulthood. J Clin Endocrinol Metab. 1984;59:551–555
  5. Azziz R, Koulianos G. Adrenal androgens and reproductive aging in females. Semin Reprod Endocrinol. 1991;9:249–260
  6. Carmina E. The role of extra-adrenal factors in adrenal androgen excess (in vivo studies). In:  Azziz R,  Nestler JE,  Dewailly D editor. Androgen excess disorders in women. Philadelphia: Lippincott-Raven; 1997;p. 425–434
  7. Azziz R, Rittmaster RS, Fox LM, Bradley EL, Potter HD, Boots LR. Role of the ovary in the adrenal androgen excess of hyperandrogenic women. Fertil Steril. 1998;69:851–859
  8. Gonzalez F, Hatala DA, Speroff L. Adrenal and ovarian steroid hormone responses to gonadotropin-releasing hormone agonist treatment in polycystic ovary syndrome. Am J Obstet Gynecol. 1991;165:535–545
  9. Hatch R, Rosenfield RL, Kim MH, Tredway D. Hirsutism (implications, etiology, and management). Am J Obstet Gynecol. 1981;140:815–830
  10. Pearlman WH, Crepy O. Steroid-protein interaction with particular reference to testosterone binding by human serum. J Biol Chem. 1967;242:182–189
  11. Ruutiainen K, Erkkola R, Grönroos MA, Kaihola HL. Androgen parameters in hirsute women (correlations with body mass index and age). Fertil Steril. 1988;50:255–259
  12. Azziz R. Glucocorticoid suppression in the treatment of androgen excess. In:  Azziz R,  Nestler JE,  Dewailly D editor. Androgen excess disorders in women. Philadelphia: Lippincott-Raven; 1997;p. 737–747

PII: S0015-0282(98)00536-6

Fertility and Sterility
Volume 71, Issue 4 , Pages 671-674 , April 1999

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