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Sperm DNA fragmentation index worsens with advancing age

  • H.S. Quant
    Affiliations
    Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Boston, MA; ReproSource, Inc., Bedford, MA; Harvard Medical School, Boston, MA; Boston IVF, Waltham, MA
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  • E. Tirado
    Affiliations
    Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Boston, MA; ReproSource, Inc., Bedford, MA; Harvard Medical School, Boston, MA; Boston IVF, Waltham, MA
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  • Q. Baca
    Affiliations
    Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Boston, MA; ReproSource, Inc., Bedford, MA; Harvard Medical School, Boston, MA; Boston IVF, Waltham, MA
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  • B. Leader
    Affiliations
    Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Boston, MA; ReproSource, Inc., Bedford, MA; Harvard Medical School, Boston, MA; Boston IVF, Waltham, MA
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  • A.S. Penzias
    Affiliations
    Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Boston, MA; ReproSource, Inc., Bedford, MA; Harvard Medical School, Boston, MA; Boston IVF, Waltham, MA
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      OBJECTIVE: To analyze the relationship between age and sperm DNA fragmentation index (DFI) as determined by the Sperm DNA Fragmentation Assay (SDFA™) in a population undergoing infertility workup.
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