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Age is highly correlated with oxidative damage in sperm from infertile males

      OBJECTIVE: Oxidative stress (OS) is strongly correlated with adverse effects on cellular lipids, proteins and DNA, which may result in defective sperm function and reduced fertility. Antioxidant capacity of semen may decrease with age which would possibly lead to increased oxidative damage, but this has not been demonstrated. This study sought to demonstrate that from infertile males have increasing frequencies of abnormal levels of lipid peroxidation (LPO), a marker of oxidative stress and DNA fragmentation.
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