Impact of failed IVF attempts: a strong negative predictor of subsequent outcome.

      Objective: Recent work has suggested that multiple failed cycles of IVF-ET are not associated with a diminished chance of success in a subsequent attempt (Fertil Steril 1998;69:1005). This report was from a compilation of SART data involving multiple IVF-ET centers. Given the inherent difficulties in evaluating pregnancy rates from multiple centers, we sought to analyze pregnancy outcome from a single center in a large cohort of patients undergoing IVF-ET specifically evaluating the impact of previous failed attempts.
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