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Embryos derived from vitrified oocytes are not at an increased risk of aneuploidy and demonstrate excellent implantation rates: a paired, randomized controlled trial (RCT) in an infertile population

  • E.J. Forman
    Affiliations
    Reproductive Endocrinology & Infertility, Reproductive Medicine Associates of New Jersey, Morristown, NJ; Obstetrics, Gynecology & Reproductive Sciences, UMDNJ-Robert Wood Johnson Medical School, New Brunswick, NJ; Genetics, Rutgers-The State University of New Jersey, Piscataway, NJ
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  • K.M. Ferry
    Affiliations
    Reproductive Endocrinology & Infertility, Reproductive Medicine Associates of New Jersey, Morristown, NJ; Obstetrics, Gynecology & Reproductive Sciences, UMDNJ-Robert Wood Johnson Medical School, New Brunswick, NJ; Genetics, Rutgers-The State University of New Jersey, Piscataway, NJ
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  • M.R. Benson
    Affiliations
    Reproductive Endocrinology & Infertility, Reproductive Medicine Associates of New Jersey, Morristown, NJ; Obstetrics, Gynecology & Reproductive Sciences, UMDNJ-Robert Wood Johnson Medical School, New Brunswick, NJ; Genetics, Rutgers-The State University of New Jersey, Piscataway, NJ
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  • J. Campos
    Affiliations
    Reproductive Endocrinology & Infertility, Reproductive Medicine Associates of New Jersey, Morristown, NJ; Obstetrics, Gynecology & Reproductive Sciences, UMDNJ-Robert Wood Johnson Medical School, New Brunswick, NJ; Genetics, Rutgers-The State University of New Jersey, Piscataway, NJ
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  • N.R. Treff
    Affiliations
    Reproductive Endocrinology & Infertility, Reproductive Medicine Associates of New Jersey, Morristown, NJ; Obstetrics, Gynecology & Reproductive Sciences, UMDNJ-Robert Wood Johnson Medical School, New Brunswick, NJ; Genetics, Rutgers-The State University of New Jersey, Piscataway, NJ
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  • R.T. Scott Jr.
    Affiliations
    Reproductive Endocrinology & Infertility, Reproductive Medicine Associates of New Jersey, Morristown, NJ; Obstetrics, Gynecology & Reproductive Sciences, UMDNJ-Robert Wood Johnson Medical School, New Brunswick, NJ; Genetics, Rutgers-The State University of New Jersey, Piscataway, NJ
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      Oocyte vitrification is emerging as a viable technology for fertility preservation and donor-oocyte banking. While promising outcomes have been reported, there remain safety concerns regarding meiotic-spindle damage with ensuing aneuploidy risk. This RCT assesses the impact of vitrification on aneuploidy and reproductive potential by comparing vitrified and control oocytes from a single patient within a single cycle and a single fresh transfer.
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