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Trophectoderm (TE) biopsy for aneuploidy screening results in lower initial hCG levels with altered predictive values: low initial levels still have high delivery rates and normal pregnancy outcomes

      Lower initial HCG (iHCG) levels 2 weeks after oocyte retrieval predict higher early pregnancy loss risk and may be used for counseling and to direct treatment. TE biopsy is becoming routine and given that it necessarily reduces initial trophoblast volume, it might alter iHCG levels and eventually placental sufficiency. This study seeks to determine whether TE biopsy impacts iHCG levels, their predictive value for delivery, and eventual newborn outcomes.
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