Reducing the burden of ART care: single blastocyst transfer after comprehensive chromosome screening (CCS) provides equivalent delivery rates, eliminates twins and lowers global health care costs

      Despite better obstetrical outcomes with singleton than twin pregnancies, elective single embryo transfer (SET) is underutilized. A recent randomized clinical trial (RCT) demonstrated that trophectoderm biopsy with CCS followed by euploid SET provides equivalent delivery rates to traditionally selected 2 embryo transfers (2ET) up through age 42 while reducing twins to 0% from 48%. This study seeks to assess the economic impact of such an approach weighing increased infertility care costs against reduced obstetrical and pediatric expenditures.
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