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Expanded carrier screening in an infertile population: how often does it impact clinical decision making?

      Options for preconception genetic screening (GS) have grown dramatically. Traditionally focused on ethnicity, it is only within the last decade that the recommended GS paradigms have included universal screening for numerous disorders. High density arrays now allow individuals’ to determine their carrier status for hundreds of genetic mutations with a single test. Literature is available on what proportion of patients will be identified as carriers for one of the panels’ screened mutations; however, very limited data exists on how often GS alters clinical management. This study seeks to determine how often large scale expanded carrier GS goes beyond providing information and actually impacts clinical care.
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