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Embryonic metabolomic analysis utilizing near infrared (NIR) spectroscopy to analyze embryos in the same cohort does not predict implantation rate: a prospective cohort study

      NIR metabolomic profiling of culture media has been assessed as a predictive tool for embryonic competence. Early validation studies were able to demonstrate statistical differences in single embryo transfers with known outcomes. These data, while provocative, were greatly limited in that they did not distinguish between embryos in the same cohort--something of paramount importance if NIR is to be used to enhance embryo selection. To address this question we evaluated the range and variability of NIR viability index (VI) results amongst double embryo transfers (DET) with 0%, 50%, and 100% implantation rates.
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