Endometrial disruption does not result in a reduced endometrial thickness or alter the proliferative pattern in a subsequent frozen embryo transfer cycle

      Evidence-based treatment options for women who fail to achieve a pregnancy with the transfer of morphologically normal embryos are limited. Endometrial disruption performed in the luteal phase preceding a transfer cycle has been proposed as an intervention to enhance pregnancy rates in these patients. While small prospective trials have shown benefit, the impact of this intervention on subsequent endometrial proliferation has not been rigorously evaluated. As an added safety measure prior to offering this technique, we sought to determine whether performing endometrial disruption would impact subsequent endometrial proliferation.
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