A mitochondrial D loop variant associated with reduced risk of embryonic aneuploidy

      Mitochondria are integral to oocyte and embryo energy production, spindle formation, and chromosomal segregation. Single nucleotide variants within the mitochondrial genome have been associated with susceptibility to many disease processes, including autoimmune and inflammatory processes. These variants could influence functions essential to early embryo development. The aim of this study was to assess if any association existed between rates of embryonic aneuploidy and sequence variants in the mitochondrial genome.
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