Sequential (Seq) vs. monophasic (Mono) media impact trial (Summit): a paired RCT comparing embryologic parameters and sustained implantation rates (SIR) amongst sibling zygotes

      Both Seq and Mono media formulations are widely utilized. Seq media consists of two phases designed to mimic in vivo conditions while Mono media is a single formulation. Mono formulations require less manipulation and are less expensive. Both formulations have attained good outcomes, but an adequately powered assessment including usable blastulation rates (USBR), ploidy risk, and SIR is lacking.
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