Formal assessment of egg donors' family histories by a genetic counselor identifies new risk factors

      The American Society for Reproductive Medicine (ASRM) recommendations for gamete donation clearly state that donors should not have significant familial disease with a genetic component.1 There are varied methods of obtaining family history from egg donor applicants in order to assess the presence or absence of significant risk. The objectives of this study were (1) to understand the impact of a formal genetic counselor risk assessment on the ultimate acceptance or denial of donor applicants, and (2) to analyze what additional family history information can be learned through this assessment beyond what is reported in industry-standard online questionnaires.
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