Advertisement

Choice of treatment to manage early miscarriage does not affect future fertility

  • Susanna M. Savukoski
    Affiliations
    Department of Obstetrics and Gynecology, Oulu University Hospital, Oulu, Finland

    PEDEGO Research Unit, University of Oulu, Oulu, Finland

    Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland
    Search for articles by this author
  • Maarit Niinimäki
    Affiliations
    Department of Obstetrics and Gynecology, Oulu University Hospital, Oulu, Finland

    PEDEGO Research Unit, University of Oulu, Oulu, Finland

    Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland
    Search for articles by this author
      The study by Tzur et al. (
      • Tzur Y.
      • Samueloff O.
      • Raz Y.
      • Bar-On S.
      • Laskov I.
      • Tzur T.
      Conception rates after medical versus surgical evacuation of early miscarriage.
      ) compared short-term fertility outcomes of surgically versus medically treated women with early miscarriage. The study population included 203 women diagnosed with early pregnancy loss. The treatment protocol was chosen based on patient preference: 106 women were treated with curettage and 97 with a medical protocol including 800 μg misoprostol. Short-term pregnancy rates and outcomes did not differ between the study groups. Pregnancy rates within 6 months median time to pregnancy, as well as pregnancy rates within 12 months and proportion of pregnancies ending in live birth, did not differ between surgically and medically managed patients. As discussed in the article, earlier studies have reported similar long-term fertility outcomes between these two protocols for treating early pregnancy loss, and the findings of short-term outcomes by Tzur et al. concur (
      • Tzur Y.
      • Samueloff O.
      • Raz Y.
      • Bar-On S.
      • Laskov I.
      • Tzur T.
      Conception rates after medical versus surgical evacuation of early miscarriage.
      ).
      To read this article in full you will need to make a payment

      References

        • Tzur Y.
        • Samueloff O.
        • Raz Y.
        • Bar-On S.
        • Laskov I.
        • Tzur T.
        Conception rates after medical versus surgical evacuation of early miscarriage.
        Fertil Steril. 2021; 115: 118-124
        • Al Wattar B.H.
        • Murugesu N.
        • Tobias A.
        • Zamora J.
        • Khan K.S.
        Management of first-trimester miscarriage: a systematic review and network meta-analysis.
        Hum Reprod Update. 2019; 25: 362-374
        • Smith L.F.P.
        • Ewings P.D.
        • Quinlan C.
        Incidence of pregnancy after expectant, medical, or surgical management of spontaneous first trimester miscarriage: long term follow-up of miscarriage treatment (MIST) randomised controlled trial.
        BMJ. 2009; 339: b3827
        • Zhang J.
        • Gilles J.M.
        • Barnhart K.
        • Creinin M.D.
        • Westhoff C.
        • Frederick M.M.
        A comparison of medical management with misoprostol and surgical management for early pregnancy failure.
        N Engl J Med. 2005; 353: 761-769
        • Niinimäki M.
        • Jouppila P.
        • Martikainen H.
        • Talvensaari-Mattila A.
        A randomized study comparing efficacy and patient satisfaction in medical or surgical treatment of miscarriage.
        Fertil Steril. 2006; 86: 367-372

      Linked Article